| 9/3/2016 | Livingstone | 3 | at | Benedict | 5 | CIAA | ||
| Kentucky State | 7 | at | Charleston Southern | 57 | @ BigS (1AA) | |||
| Tuskegee | 36 | at | Clark Atlanta | 13 | ||||
| Central State | 19 | at | Dayton | 31 | @ Pio (1AA) | |||
| Morehouse | 19 | at | Edward Waters | 13 | @ Sun (NAIA) | |||
| Texas College | 6 | at | Lane | 44 | CSFL (NAIA) | |||
| Albany State GA | 7 | at | Valdosta State | 16 | @ GSC | |||
| 9/4/2016 | Fort Valley State | 21 | vs | Miles | 34 | Birmingham AL | ||
| 9/10/2016 | Tuskegee | 28 | vs | Albany State GA | 18 | Phenix City AL | ||
| Limestone | 19 | at | Benedict | 13 | D2Ind | |||
| Clark Atlanta | 20 | vs | Central State | 13 | Chicago IL | |||
| Fort Valley State | 7 | at | Lane | 10 | ||||
| West Georgia | 29 | at | Miles | 0 | GSC | |||
| Kentucky State | 3 | at | Morehouse | 14 | ||||
| 9/17/2016 | Benedict | 42 | at | Central State | 6 | |||
| Morehouse | 30 | vs | Elizabeth City State | 35 | Rocky Mount NC | vs CIAA | ||
| Clark Atlanta | 31 | at | Fort Valley State | 37 | 3OT | |||
| Virginia State | 20 | at | Kentucky State | 7 | CIAA | |||
| Lane | 46 | at | Langston | 44 | @ CSFL (NAIA) | |||
| Albany State GA | 24 | at | Southeastern FL | 2 | @ Sun (NAIA) | |||
| Florida A&M | 17 | vs | Tuskegee | 20 | Mobile AL | vs MEAC (1AA) | ||
| 9/24/2016 | West Georgia | 27 | at | Albany State GA | 23 | GSC | ||
| Fort Valley State | 14 | at | Benedict | 28 | ||||
| Kentucky State | 17 | vs | Central State | 14 | Indianapolis IN | |||
| Ave Maria | 13 | at | Clark Atlanta | 37 | Sun (NAIA) | |||
| Miles | 31 | at | Morehouse | 7 | ||||
| Lane | 7 | at | Tuskegee | 38 | ||||
| 10/1/2016 | Miles | 33 | at | Albany State GA | 35 | |||
| Fort Valley State | 9 | at | Alderson-Broaddus | 33 | @ D2Ind | |||
| Morehouse | 36 | at | Clark Atlanta | 37 | ||||
| Benedict | 0 | at | Gardner-Webb | 45 | @ BigS (1AA) | |||
| Central State | 7 | at | Kentucky Wesleyan | 21 | @ D2Ind | |||
| Lane | 9 | at | Lincoln MO | 12 | @ GLV | |||
| UNC Pembroke | 16 | at | Tuskegee | 21 | D2Ind | |||
| Kentucky State | 10 | vs | Valdosta State | 48 | Waycross GA | vs GSC | ||
| 10/6/2016 | Clark Atlanta | 27 | at | Shorter | 23 | @ GSC | ||
| 10/8/2016 | Kentucky State | 26 | at | Fort Valley State | 10 | |||
| Benedict | 18 | at | Lane | 19 | ||||
| Central State | 0 | at | Miles | 36 | ||||
| Tuskegee | 28 | vs | Morehouse | 19 | Columbus GA | |||
| 10/15/2016 | Lane | 10 | at | Central State | 27 | |||
| Benedict | 14 | at | Clark Atlanta | 27 | ||||
| Fort Valley State | 14 | at | Florida Tech | 48 | @ GSC | |||
| Miles | 24 | at | Kentucky State | 28 | ||||
| Albany State GA | 26 | at | Morehouse | 21 | ||||
| 10/22/2016 | Clark Atlanta | 7 | at | Albany State GA | 17 | |||
| Morehouse | 10 | at | Benedict | 13 | ||||
| Central State | 28 | at | Fort Valley State | 30 | ||||
| Miles | 26 | at | Lane | 14 | ||||
| Kentucky State | 10 | at | Tuskegee | 9 | ||||
| 10/29/2016 | Albany State GA | 34 | vs | Benedict | 7 | Augusta GA | ||
| Tuskegee | 42 | at | Central State | 14 | ||||
| Miles | 34 | at | Clark Atlanta | 17 | ||||
| Lane | 35 | at | Kentucky State | 21 | ||||
| Fort Valley State | 24 | at | Morehouse | 16 | ||||
| 11/5/2016 | Fort Valley State | 21 | vs | Albany State GA | 17 | Columbus GA | ||
| Southwest Baptist | 54 | at | Central State | 34 | GLV | |||
| Clark Atlanta | 0 | at | Kennesaw St | 56 | @ BigS (1AA) | |||
| Benedict | 39 | at | Kentucky State | 35 | ||||
| Morehouse | 24 | at | Lane | 21 | ||||
| Tuskegee | 13 | at | Miles | 10 | ||||
| 11/12/2016 | Point | 22 | at | Benedict | 7 | Sun (NAIA) | ||
| Fort Valley State | 33 | at | Kentucky State | 30 | 2OT | |||
| Virginia State | 45 | at | Tuskegee | 35 | CIAA | |||
| 11/19/2016 | Tuskegee | 35 | at | Newberry | 33 | @ SAC | ||
| 11/24/2016 | Miles | 20 | at | Alabama State | 53 | @ SWAC (1AA) | ||
| 11/26/2016 | Tuskegee | 26 | at | North Greenville | 45 | @ D2Ind |