| 9/3/2015 | Colorado | 20 | at | Hawaii (3-10) | 28 | at MW | ||
| 9/12/2015 | Massachusetts (3-9) | 14 | at | Colorado | 48 | MAC | ||
| 9/19/2015 | Colorado State (7-6) | 24 | at | Colorado | 27 | OT | Denver CO | MW |
| 9/26/2015 | Nicholls State (3-8) | 0 | at | Colorado | 48 | SLC (1AA) | ||
| 10/3/2015 | Oregon (9-4,7-2) | 41 | at | Colorado | 24 | |||
| 10/10/2015 | Colorado | 23 | at | Arizona State (6-7,4-5) | 48 | |||
| 10/17/2015 | Arizona (7-6,3-6) | 38 | at | Colorado | 31 | |||
| 10/24/2015 | Colorado | 17 | at | Oregon State (2-10,0-9) | 13 | |||
| 10/31/2015 | Colorado | 31 | at | UCLA (8-5,5-4) | 35 | |||
| 11/7/2015 | Stanford (12-2,9-1) | 42 | at | Colorado | 10 | |||
| 11/13/2015 | Southern California (8-6,6-4) | 27 | at | Colorado | 24 | |||
| 11/21/2015 | Colorado | 3 | at | Washington State (9-4,6-3) | 27 | |||
| 11/28/2015 | Colorado | 14 | at | Utah (10-3,6-3) | 20 |
| vs Colorado | vs Other Opponents | Colorado compared to OOs | |
| Record: | 9-4 | 78-76 | |
| Points Scored: | 27.46 | 30.29 | 2.83 |
| Points Allowed: | 24.62 | 30.65 | -6.03 |
| Margin: | 2.84 | -0.36 | -3.20 |
| Total Points: | 52.08 | 60.94 | -8.86 |