| 9/1/2012 | Maryville | 33 | at | Huntingdon AL (6-3) | 49 | at D3Ind | ||
| 9/8/2012 | Emory & Henry (6-4) | 21 | at | Maryville | 8 | ODC | ||
| 9/15/2012 | Sewanee (3-7) | 17 | at | Maryville | 24 | SCAC | ||
| 9/29/2012 | Christopher Newport (6-5,5-2) | 45 | at | Maryville | 31 | |||
| 10/6/2012 | Maryville | 41 | at | Greensboro (5-5,3-4) | 6 | |||
| 10/13/2012 | Maryville | 28 | at | Methodist (5-5,4-3) | 24 | |||
| 10/20/2012 | LaGrange (3-7,3-4) | 17 | at | Maryville | 13 | |||
| 10/27/2012 | Maryville | 31 | at | Averett (1-9,1-6) | 7 | |||
| 11/3/2012 | North Carolina Wesleyan (3-7,2-5) | 13 | at | Maryville | 34 | |||
| 11/10/2012 | Maryville | 22 | at | Ferrum (7-3,5-2) | 17 |
| vs Maryville | vs Other Opponents | Maryville compared to OOs | |
| Record: | 4-6 | 41-49 | |
| Points Scored: | 21.60 | 23.68 | 2.08 |
| Points Allowed: | 26.50 | 27.01 | -0.51 |
| Margin: | -4.90 | -3.33 | 1.57 |
| Total Points: | 48.10 | 50.69 | -2.59 |