| 9/1/2012 | Washington & Jefferson (8-3) | 23 | at | Methodist | 6 | TPAC | ||
| 9/8/2012 | Methodist | 34 | at | Guilford (5-5) | 21 | at ODC | ||
| 9/15/2012 | Methodist | 20 | at | Emory & Henry (6-4) | 34 | at ODC | ||
| 9/29/2012 | Greensboro (5-5,3-4) | 34 | at | Methodist | 33 | |||
| 10/6/2012 | Methodist | 34 | at | North Carolina Wesleyan (3-7,2-5) | 13 | |||
| 10/13/2012 | Maryville (6-4,5-2) | 28 | at | Methodist | 24 | |||
| 10/20/2012 | Ferrum (7-3,5-2) | 21 | at | Methodist | 13 | |||
| 10/27/2012 | Methodist | 26 | at | LaGrange (3-7,3-4) | 23 | |||
| 11/3/2012 | Averett (1-9,1-6) | 27 | at | Methodist | 33 | 2OT | ||
| 11/10/2012 | Methodist | 30 | at | Christopher Newport (6-5,5-2) | 29 |
| vs Methodist | vs Other Opponents | Methodist compared to OOs | |
| Record: | 5-5 | 45-47 | |
| Points Scored: | 25.30 | 22.72 | -2.58 |
| Points Allowed: | 25.30 | 27.05 | -1.75 |
| Margin: | 0.00 | -4.33 | -4.33 |
| Total Points: | 50.60 | 49.77 | 0.83 |