| 9/1/2012 | Indiana State | 17 | at | Indiana (4-8) | 24 | at B10 | ||
| 9/8/2012 | Quincy (3-8) | 0 | at | Indiana State | 44 | GLV (D2) | ||
| 9/15/2012 | Drake (8-3) | 10 | at | Indiana State | 27 | Pio | ||
| 9/22/2012 | South Dakota State (9-4,6-3) | 24 | at | Indiana State | 10 | |||
| 9/29/2012 | Indiana State | 24 | at | Southern Illinois (6-5,5-3) | 3 | |||
| 10/6/2012 | Missouri State (3-8,3-5) | 17 | at | Indiana State | 31 | |||
| 10/13/2012 | Indiana State | 17 | at | North Dakota State (14-1,8-1) | 14 | |||
| 10/20/2012 | Indiana State | 23 | at | Western Illinois (3-8,1-7) | 7 | |||
| 10/27/2012 | South Dakota (1-10,0-8) | 14 | at | Indiana State | 45 | |||
| 11/3/2012 | Illinois State (9-4,5-3) | 17 | at | Indiana State | 10 | |||
| 11/17/2012 | Indiana State | 6 | at | Youngstown State (7-4,4-4) | 27 |
| vs Indiana State | vs Other Opponents | Indiana State compared to OOs | |
| Record: | 4-7 | 63-56 | |
| Points Scored: | 14.27 | 25.04 | 10.77 |
| Points Allowed: | 23.09 | 24.39 | -1.30 |
| Margin: | -8.82 | 0.65 | 9.47 |
| Total Points: | 37.36 | 49.43 | -12.07 |