| 9/1/2012 | Michigan | 14 | vs | Alabama (13-1) | 41 | Arlington TX | vs SEC | |
| 9/8/2012 | Air Force (6-7) | 25 | at | Michigan | 31 | MW | ||
| 9/15/2012 | Massachusetts (1-11) | 13 | at | Michigan | 63 | MAC | ||
| 9/22/2012 | Michigan | 6 | at | Notre Dame (12-1) | 13 | at ND | ||
| 10/6/2012 | Michigan | 44 | at | Purdue (6-7,3-5) | 13 | |||
| 10/13/2012 | Illinois (2-10,0-8) | 0 | at | Michigan | 45 | |||
| 10/20/2012 | Michigan State (7-6,3-5) | 10 | at | Michigan | 12 | |||
| 10/27/2012 | Michigan | 9 | at | Nebraska (10-4,7-2) | 23 | |||
| 11/3/2012 | Michigan | 35 | at | Minnesota (6-7,2-6) | 13 | |||
| 11/10/2012 | Northwestern (10-3,5-3) | 31 | at | Michigan | 38 | OT | ||
| 11/17/2012 | Iowa (4-8,2-6) | 17 | at | Michigan | 42 | |||
| 11/24/2012 | Michigan | 21 | at | Ohio State (12-0,8-0) | 26 | |||
| 1/1/2013 | South Carolina (11-2) | 33 | vs | Michigan | 28 | Outback Bowl | SEC |
| vs Michigan | vs Other Opponents | Michigan compared to OOs | |
| Record: | 5-8 | 95-59 | |
| Points Scored: | 19.85 | 27.49 | 7.64 |
| Points Allowed: | 29.85 | 23.18 | 6.67 |
| Margin: | -10.00 | 4.31 | 14.31 |
| Total Points: | 49.70 | 50.67 | -0.97 |