| 9/1/2012 | Missouri State (3-8) | 9 | at | Kansas State | 51 | MVC (1AA) | ||
| 9/8/2012 | Miami-Florida (7-5) | 13 | at | Kansas State | 52 | ACC | ||
| 9/15/2012 | North Texas (4-8) | 21 | at | Kansas State | 35 | SBC | ||
| 9/22/2012 | Kansas State | 24 | at | Oklahoma (10-3,8-1) | 19 | |||
| 10/6/2012 | Kansas (1-11,0-9) | 16 | at | Kansas State | 56 | |||
| 10/13/2012 | Kansas State | 27 | at | Iowa State (6-7,3-6) | 21 | |||
| 10/20/2012 | Kansas State | 55 | at | West Virginia (7-6,4-5) | 14 | |||
| 10/27/2012 | Texas Tech (8-5,4-5) | 24 | at | Kansas State | 55 | |||
| 11/3/2012 | Oklahoma State (8-5,5-4) | 30 | at | Kansas State | 44 | |||
| 11/10/2012 | Kansas State | 23 | at | TCU (7-6,4-5) | 10 | |||
| 11/17/2012 | Kansas State | 24 | at | Baylor (8-5,4-5) | 52 | |||
| 12/1/2012 | Texas (9-4,5-4) | 24 | at | Kansas State | 42 | |||
| 1/3/2013 | Oregon (12-1) | 34 | vs | Kansas State | 17 | Tostitos Fiesta Bowl | P12 |
| vs Kansas State | vs Other Opponents | Kansas State compared to OOs | |
| Record: | 2-11 | 88-63 | |
| Points Scored: | 22.08 | 34.54 | 12.46 |
| Points Allowed: | 38.85 | 28.25 | 10.60 |
| Margin: | -16.77 | 6.29 | 23.06 |
| Total Points: | 60.93 | 62.79 | -1.86 |