| 8/30/2008 | Texas College NAIA | 0 | @ | MS Valley St | 38 | ||||
| 9/13/2008 | MS Valley St | 7 | @ | Southern Univ | 49 | SWAC | |||
| 9/20/2008 | Prairie View | 49 | @ | MS Valley St | 15 | SWAC | |||
| 9/25/2008 | MS Valley St | 7 | @ | Alabama St | 47 | SWAC | |||
| 10/11/2008 | Alcorn St | 35 | @ | MS Valley St | 21 | SWAC | |||
| 10/18/2008 | Savannah St | 20 | @ | MS Valley St | 22 | ||||
| 10/25/2008 | MS Valley St | 27 | @ | Jackson St | 29 | SWAC | |||
| 11/1/2008 | Grambling | 35 | @ | MS Valley St | 14 | SWAC | |||
| 11/8/2008 | MS Valley St | 58 | @ | Texas Southern | 44 | SWAC | |||
| 11/15/2008 | MS Valley St | 0 | @ | Ark Pine Bluff | 34 | SWAC | |||
| 11/22/2008 | Alabama A&M | 58 | @ | MS Valley St | 23 | SWAC |