| 9/4/2005 | #11 West Virginia | 15 | @ | Syracuse | 7 | BigE | |||
| 9/10/2005 | Wofford | 7 | @ | #11 West Virginia | 35 | ||||
| 9/17/2005 | #11 West Virginia | 31 | @ | Maryland | 19 | ||||
| 9/24/2005 | East Carolina | 15 | @ | #11 West Virginia | 20 | ||||
| 10/1/2005 | #11 Virginia Tech | 34 | @ | #11 West Virginia | 17 | ||||
| 10/8/2005 | #11 West Virginia | 27 | @ | Rutgers | 14 | BigE | |||
| 10/15/2005 | #15 Louisville | 44 | @ | #11 West Virginia | 46 | 3 OT | BigE | ||
| 11/2/2005 | Connecticut | 13 | @ | #11 West Virginia | 45 | BigE | |||
| 11/9/2005 | #11 West Virginia | 38 | @ | Cincinnati | 0 | BigE | |||
| 11/24/2005 | Pittsburgh | 13 | @ | #11 West Virginia | 45 | BigE | |||
| 12/3/2005 | #11 West Virginia | 28 | @ | South Florida | 13 | BigE | |||
| 1/2/2006 | #8 Georgia | 35 | vs | #11 West Virginia | 38 | Sugar |