| 8/28/2021 | Evangel | 24 | at | Clarke (1-10,1-10) | 9 | |||
| 9/4/2021 | Graceland (0-11,0-11) | 0 | at | Evangel | 62 | |||
| 9/11/2021 | Evangel | 35 | at | Culver-Stockton (8-3,8-3) | 38 | |||
| 9/17/2021 | William Penn (3-8,3-8) | 14 | at | Evangel | 28 | |||
| 9/25/2021 | Evangel | 6 | at | Grand View (14-1,11-0) | 23 | |||
| 10/2/2021 | Peru State (7-4,7-4) | 23 | at | Evangel | 22 | |||
| 10/16/2021 | Evangel | 30 | at | Missouri Valley (3-8,3-8) | 23 | |||
| 10/23/2021 | Baker (9-2,9-2) | 34 | at | Evangel | 21 | |||
| 10/30/2021 | Evangel | 37 | at | MidAmerica Nazarene (3-8,3-8) | 29 | |||
| 11/6/2021 | Benedictine KS (7-4,7-4) | 34 | at | Evangel | 0 | |||
| 11/13/2021 | Central Methodist (9-3,9-2) | 17 | at | Evangel | 7 |
| vs Evangel | vs Other Opponents | Evangel compared to OOs | |
| Record: | 6-5 | 58-57 | |
| Points Scored: | 22.18 | 29.17 | 6.99 |
| Points Allowed: | 24.73 | 29.00 | -4.27 |
| Margin: | -2.55 | 0.17 | 2.72 |
| Total Points: | 46.91 | 58.17 | -11.26 |