| 9/18/2021 | Wesleyan | 21 | at | Colby (4-5,4-5) | 5 | |||
| 9/25/2021 | Hamilton (2-7,2-7) | 14 | at | Wesleyan | 30 | |||
| 10/2/2021 | Wesleyan | 27 | at | Bates (3-6,3-6) | 24 | |||
| 10/9/2021 | Bowdoin (1-8,1-8) | 35 | at | Wesleyan | 38 | |||
| 10/16/2021 | Wesleyan | 36 | at | Tufts (4-5,4-5) | 35 | |||
| 10/23/2021 | Middlebury (3-6,3-6) | 0 | at | Wesleyan | 24 | |||
| 10/30/2021 | Amherst (5-4,5-4) | 16 | at | Wesleyan | 14 | 4OT | ||
| 11/6/2021 | Wesleyan | 0 | at | Williams (9-0,9-0) | 25 | |||
| 11/13/2021 | Trinity CT (8-1,8-1) | 14 | at | Wesleyan | 7 |
| vs Wesleyan | vs Other Opponents | Wesleyan compared to OOs | |
| Record: | 3-6 | 36-36 | |
| Points Scored: | 18.67 | 21.47 | 2.80 |
| Points Allowed: | 21.89 | 21.47 | 0.42 |
| Margin: | -3.22 | 0.00 | 3.22 |
| Total Points: | 40.56 | 42.94 | -2.38 |