| 9/18/2021 | Tufts | 28 | at | Trinity CT (8-1,8-1) | 42 | |||
| 9/25/2021 | Williams (9-0,9-0) | 32 | at | Tufts | 29 | OT | ||
| 10/2/2021 | Tufts | 21 | at | Amherst (5-4,5-4) | 24 | |||
| 10/9/2021 | Bates (3-6,3-6) | 33 | at | Tufts | 10 | |||
| 10/16/2021 | Wesleyan (6-3,6-3) | 36 | at | Tufts | 35 | |||
| 10/23/2021 | Tufts | 25 | at | Bowdoin (1-8,1-8) | 13 | |||
| 10/30/2021 | Tufts | 30 | at | Hamilton (2-7,2-7) | 24 | OT | ||
| 11/6/2021 | Colby (4-5,4-5) | 21 | at | Tufts | 26 | |||
| 11/13/2021 | Tufts | 34 | at | Middlebury (3-6,3-6) | 27 |
| vs Tufts | vs Other Opponents | Tufts compared to OOs | |
| Record: | 5-4 | 36-36 | |
| Points Scored: | 28.00 | 19.74 | -8.26 |
| Points Allowed: | 26.44 | 19.74 | 6.70 |
| Margin: | 1.56 | 0.00 | -1.56 |
| Total Points: | 54.44 | 39.48 | 14.96 |