9/3/2015 | Alcorn State | 6 | at | Georgia Tech | 69 | | | @ ACC (1A) |
9/5/2015 | Grambling | 14 | at | California | 73 | | | @ P12 (1A) |
| Alabama A&M | 10 | at | Cincinnati | 52 | | | @ AAC (1A) |
| Southern | 15 | at | Louisiana Tech | 62 | | | @ CUSA (1A) |
| Jackson State | 14 | at | Middle Tenn State | 70 | | | @ CUSA (1A) |
| Mississippi Valley State | 0 | at | New Mexico | 66 | | | @ MW (1A) |
| Prairie View | 38 | at | Texas Southern | 11 | | | |
9/6/2015 | Ark Pine Bluff | 7 | vs | South Carolina State | 35 | | Orlando FL | vs MEAC |
| Alabama State | 14 | at | Tennessee State | 24 | | | @ OVC |
9/10/2015 | Southern | 50 | at | Mississippi Valley State | 13 | | | |
9/11/2015 | Bacone | 0 | at | Texas Southern | 63 | | | CSFL (NAIA) |
9/12/2015 | Alcorn State | 31 | at | Alabama State | 14 | | | |
| Morehouse | 27 | at | Ark Pine Bluff | 29 | 3OT | | SIAC (D2) |
| Bethune-Cookman | 56 | at | Grambling | 53 | | | MEAC |
| Jackson State | 25 | vs | Tennessee State | 35 | | Memphis TN | vs OVC |
| Prairie View | 24 | at | Texas State | 63 | | | @ SBC (1A) |
9/19/2015 | Grambling | 14 | at | Alabama State | 10 | | | |
| Mississippi Valley State | 14 | at | Alcorn State | 55 | | | |
| Texas Southern | 24 | at | Ark Pine Bluff | 20 | | | |
| Alabama A&M | 49 | at | Prairie View | 53 | | | |
| Jackson State | 31 | at | Southern | 50 | | | |
9/26/2015 | Ark Pine Bluff | 9 | at | Alabama A&M | 28 | | | |
| Concordia AL | 0 | at | Alcorn State | 47 | | | None (Unk?) |
| Southern | 6 | at | Georgia | 48 | | | @ SEC (1A) |
| Texas Southern | 30 | at | Jackson State | 34 | | | |
| Alabama State | 45 | at | Mississippi Valley State | 15 | | | |
| Grambling | 70 | vs | Prairie View | 54 | | Dallas TX | |
10/1/2015 | Alabama State | 41 | at | Texas Southern | 23 | | | |
10/3/2015 | Alcorn State | 61 | vs | Ark Pine Bluff | 14 | | Little Rock AR | |
| Alabama A&M | 0 | at | Coastal Carolina | 55 | | | @ BigS |
| Grambling | 59 | at | Jackson State | 27 | | | |
| Mississippi Valley State | 7 | at | Jacksonville State | 49 | | | @ OVC |
10/10/2015 | Southern | 45 | at | Alabama State | 34 | | | |
| Alabama A&M | 14 | at | Grambling | 37 | | | |
| Mississippi Valley State | 6 | at | Prairie View | 45 | | | |
10/15/2015 | Alabama State | 31 | at | Ark Pine Bluff | 24 | | | |
10/17/2015 | Jackson State | 22 | at | Alabama A&M | 28 | | | |
| Grambling | 35 | at | Alcorn State | 34 | OT | | |
| Texas Southern | 49 | at | Mississippi Valley State | 21 | | | |
| Prairie View | 47 | at | Southern | 42 | | | |
10/24/2015 | Mississippi Valley State | 14 | at | Grambling | 49 | | | |
| Ark Pine Bluff | 3 | at | Jackson State | 37 | | | |
| Southern | 40 | at | Texas Southern | 21 | | | |
10/31/2015 | Alabama A&M | 20 | vs | Alabama State | 35 | | Birmingham AL | |
| Jackson State | 23 | at | Mississippi Valley State | 16 | | | |
| Ark Pine Bluff | 29 | at | Prairie View | 54 | | | |
| Alcorn State | 48 | at | Southern | 7 | | | |
11/7/2015 | Mississippi Valley State | 24 | at | Alabama A&M | 27 | OT | | |
| Prairie View | 40 | at | Alcorn State | 34 | | | |
| Southern | 57 | at | Ark Pine Bluff | 24 | | | |
| Texas Southern | 15 | at | Grambling | 41 | | | |
| Alabama State | 17 | at | Jackson State | 12 | | | |
11/14/2015 | Prairie View | 38 | at | Alabama State | 13 | | | |
| Grambling | 49 | at | Ark Pine Bluff | 31 | | | |
| Alabama A&M | 7 | at | Southern | 46 | | | |
| Alcorn State | 65 | at | Texas Southern | 13 | | | |
11/21/2015 | Miles | 7 | at | Alabama State | 26 | | | SIAC (D2) |
| Alabama A&M | 10 | at | Alcorn State | 44 | | | |
| Ark Pine Bluff | 25 | at | Mississippi Valley State | 19 | OT | | |
| Jackson State | 14 | at | Prairie View | 56 | | | |
11/28/2015 | Texas Southern | 7 | at | Alabama A&M | 38 | | | |
| Southern | 23 | vs | Grambling | 34 | | New Orleans LA | |
| Alcorn State | 14 | at | Jackson State | 10 | | | |
12/5/2015 | Grambling | 21 | vs | Alcorn State | 49 | | SWAC Championship (Houston TX) | |
12/19/2015 | Alcorn State | 34 | vs | North Carolina A&T | 41 | | Air Force Reserve Celebration Bowl (Atlanta GA) | vs MEAC |