| 9/1/2012 | Jacksonville State | 24 | at | Arkansas (4-8) | 49 | at SEC | ||
| 9/8/2012 | Chattanooga (6-5) | 24 | at | Jacksonville State | 27 | SoCon | ||
| 9/22/2012 | Jacksonville State | 21 | at | Eastern Kentucky (8-3,6-2) | 51 | |||
| 9/29/2012 | SE Missouri State (3-8,2-6) | 16 | at | Jacksonville State | 31 | |||
| 10/6/2012 | Jacksonville State | 37 | at | Tennessee Tech (3-8,1-7) | 28 | |||
| 10/13/2012 | Jacksonville State | 28 | at | Eastern Illinois (7-5,6-1) | 31 | |||
| 10/20/2012 | Tennessee State (8-3,4-3) | 28 | at | Jacksonville State | 31 | OT | ||
| 10/27/2012 | Murray State (5-6,4-4) | 35 | at | Jacksonville State | 38 | |||
| 11/3/2012 | Jacksonville State | 47 | at | Tennessee-Martin (8-3,6-2) | 49 | |||
| 11/10/2012 | Austin Peay (2-9,1-7) | 23 | at | Jacksonville State | 38 | |||
| 11/17/2012 | Jacksonville State | 0 | at | Florida (11-2) | 23 | at SEC |
| vs Jacksonville State | vs Other Opponents | Jacksonville State compared to OOs | |
| Record: | 5-6 | 60-54 | |
| Points Scored: | 32.45 | 28.97 | -3.48 |
| Points Allowed: | 29.27 | 29.75 | -0.48 |
| Margin: | 3.18 | -0.78 | -3.96 |
| Total Points: | 61.72 | 58.72 | 3.00 |