| 9/1/2011 | Illinois State Redbirds 26 @ Eastern Illinois 33 | |
| 9/10/2011 | Eastern Illinois 21 @ Northwestern Wildcats 42 | |
| 9/17/2011 | Tennessee Tech Golden Eagles 31 @ Eastern Illinois 20 | † |
| 9/24/2011 | Eastern Illinois 21 @ Jacksonville State Gamecocks 28 | † |
| 10/1/2011 | Eastern Illinois 30 @ SE Missouri State Redhawks 37 | † |
| 10/8/2011 | Eastern Kentucky Colonels 48 @ Eastern Illinois 16 | † |
| 10/15/2011 | Eastern Illinois 27 @ Murray State Racers 36 | † |
| 10/22/2011 | Tennessee-Martin Skyhawks 24 @ Eastern Illinois 23 | † |
| 10/29/2011 | Eastern Illinois 19 @ Austin Peay Governers 10 | † |
| 11/5/2011 | Tennessee State Tigers 18 @ Eastern Illinois 17 | † |
| 11/12/2011 | Eastern Illinois 28 @ Southern Illinois Salukis 45 |