| 9/1/2011 | Illinois State 26 @ Eastern Illinois Panthers 33 | |
| 9/10/2011 | Morehead State Eagles 21 @ Illinois State 52 | |
| 9/17/2011 | Illinois State 27 @ Youngstown State Penguins 34 | † |
| 9/24/2011 | South Dakota State Jackrabbits 13 @ Illinois State 20 | † |
| 10/1/2011 | Illinois State 10 @ North Dakota State Bison 20 | † |
| 10/8/2011 | Illinois State 38 @ Missouri State Bears 13 | † |
| 10/15/2011 | South Dakota Coyotes 3 @ Illinois State 28 | |
| 10/22/2011 | Indiana State Sycamores 14 @ Illinois State 17 | † |
| 10/29/2011 | Illinois State 38 @ Southern Illinois Salukis 30 | † |
| 11/5/2011 | Western Illinois Leathernecks 7 @ Illinois State 31 | † |
| 11/19/2011 | Northern Iowa Panthers 23 @ Illinois State 20 1OT | † |