| 9/4/2010 | Fitchburg State Falcons 15 @ UMass Dartmouth 37 | † |
| 9/11/2010 | UMass Dartmouth 7 @ Bridgewater State MA Bears 10 | † |
| 9/18/2010 | UMass Dartmouth 0 @ Maine Maritime Mariners 42 | † |
| 9/25/2010 | Plymouth State Panthers 33 @ UMass Dartmouth 9 | † |
| 10/2/2010 | UMass Dartmouth 14 @ MIT Engineers 6 | † |
| 10/9/2010 | Salve Regina Seahawks 28 @ UMass Dartmouth 6 | † |
| 10/16/2010 | UMass Dartmouth 9 @ Nichols Bison 7 | † |
| 10/23/2010 | Endicott Power Gulls 37 @ UMass Dartmouth 13 | † |
| 10/30/2010 | Curry Colonels 28 @ UMass Dartmouth 10 | † |
| 11/6/2010 | UMass Dartmouth 14 @ Western New England Golden Bears 37 | † |