| 8/31/2024 | Virginia Tech (6-6) | 27 | at | Vanderbilt | 34 | ACC | ||
| 9/7/2024 | Alcorn State (6-6) | 0 | at | Vanderbilt | 55 | SWAC (1AA) | ||
| 9/14/2024 | Vanderbilt | 32 | at | Georgia State (3-9) | 36 | at SBC | ||
| 9/21/2024 | Vanderbilt | 27 | at | Missouri (9-3,5-3) | 30 | |||
| 10/5/2024 | Alabama (9-3,5-3) | 35 | at | Vanderbilt | 40 | |||
| 10/12/2024 | Vanderbilt | 20 | at | Kentucky (4-8,1-7) | 13 | |||
| 10/19/2024 | Ball State (3-9) | 14 | at | Vanderbilt | 24 | MAC | ||
| 10/26/2024 | Texas (12-2,7-2) | 27 | at | Vanderbilt | 24 | |||
| 11/2/2024 | Vanderbilt | 17 | at | Auburn (5-7,2-6) | 7 | |||
| 11/9/2024 | South Carolina (9-3,5-3) | 28 | at | Vanderbilt | 7 | |||
| 11/23/2024 | Vanderbilt | 17 | at | LSU (8-4,5-3) | 24 | |||
| 11/30/2024 | Tennessee (10-3,6-2) | 36 | at | Vanderbilt | 23 | |||
| 12/27/2024 | Georgia Tech (7-5) | vs | Vanderbilt | Birmingham Bowl - Birmingham AL | ACC |
| vs Vanderbilt | vs Other Opponents | Vanderbilt compared to OOs | |
| Record: | 6-6 | 85-62 | |
| Points Scored: | 23.08 | 29.28 | 6.20 |
| Points Allowed: | 26.67 | 22.70 | 3.97 |
| Margin: | -3.59 | 6.58 | 10.17 |
| Total Points: | 49.75 | 51.98 | -2.23 |