| 8/29/2024 | Fordham | 17 | at | Bowling Green | 41 | Pat (1AA) | ||
| Lafayette | 13 | at | Buffalo | 30 | Pat (1AA) | |||
| Central Conn | 10 | at | Central Michigan | 66 | NE (1AA) | |||
| Duquesne | 10 | at | Toledo | 49 | NE (1AA) | |||
| 8/30/2024 | Western Michigan | 14 | at | Wisconsin | 28 | @ B10 | ||
| 8/31/2024 | Eastern Michigan | 28 | at | Massachusetts | 14 | @ Ind | ||
| Western Illinois | 15 | at | Northern Illinois | 54 | BigS (1AA) | |||
| Miami-Ohio | 6 | at | Northwestern | 13 | @ B10 | |||
| Akron | 6 | at | Ohio State | 52 | @ B10 | |||
| Kent State | 24 | at | Pittsburgh | 55 | @ ACC | |||
| Ohio | 22 | at | Syracuse | 38 | @ ACC | |||
| 9/7/2024 | Missouri State | 34 | at | Ball State | 42 | MVC (1AA) | ||
| Central Michigan | 16 | at | Florida Intl | 52 | @ CUSA | |||
| St Francis PA | 23 | at | Kent State | 17 | NE (1AA) | |||
| Buffalo | 0 | at | Missouri | 38 | @ SEC | |||
| Northern Illinois | 16 | at | Notre Dame | 14 | @ ND | |||
| Western Michigan | 0 | at | Ohio State | 56 | @ B10 | |||
| South Alabama | 20 | at | Ohio | 27 | SBC | |||
| Bowling Green | 27 | at | Penn State | 34 | @ B10 | |||
| Akron | 17 | at | Rutgers | 49 | @ B10 | |||
| Massachusetts | 23 | at | Toledo | 38 | Ind | |||
| Eastern Michigan | 9 | at | Washington | 30 | @ B10 | |||
| 9/14/2024 | Colgate | 20 | at | Akron | 31 | Pat (1AA) | ||
| Massachusetts | 3 | at | Buffalo | 34 | Ind | |||
| Jacksonville State | 34 | at | Eastern Michigan | 37 | CUSA | |||
| Central Michigan | 9 | at | Illinois | 30 | @ B10 | |||
| Ball State | 0 | at | Miami-Florida | 62 | @ ACC | |||
| Cincinnati | 27 | at | Miami-Ohio | 16 | B12 | |||
| Toledo | 41 | at | Mississippi State | 17 | @ SEC | |||
| Morgan State | 6 | at | Ohio | 21 | MEAC (1AA) | |||
| Kent State | 0 | at | Tennessee | 71 | @ SEC | |||
| Bethune-Cookman | 31 | at | Western Michigan | 59 | SWAC (1AA) | |||
| 9/21/2024 | Ball State | 34 | at | Central Michigan | 37 | |||
| St Francis PA | 0 | at | Eastern Michigan | 36 | NE (1AA) | |||
| Ohio | 6 | at | Kentucky | 41 | @ SEC | |||
| Buffalo | 23 | at | Northern Illinois | 20 | ||||
| Miami-Ohio | 3 | at | Notre Dame | 28 | @ ND | |||
| Kent State | 0 | at | Penn State | 56 | @ B10 | |||
| Akron | 7 | at | South Carolina | 50 | @ SEC | |||
| Bowling Green | 20 | at | Texas A&M | 26 | @ SEC | |||
| Toledo | 21 | at | Western Kentucky | 26 | @ CUSA | |||
| 9/28/2024 | Old Dominion | 30 | at | Bowling Green | 27 | SBC | ||
| San Diego State | 21 | at | Central Michigan | 22 | MW | |||
| Buffalo | 3 | at | Connecticut | 47 | @ Ind | |||
| Ball State | 7 | at | James Madison | 63 | @ SBC | |||
| Eastern Michigan | 52 | at | Kent State | 33 | ||||
| Western Michigan | 20 | at | Marshall | 27 | @ SBC | |||
| Massachusetts | 20 | at | Miami-Ohio | 23 | Ind | |||
| Northern Illinois | 17 | at | North Carolina State | 24 | @ ACC | |||
| Akron | 10 | at | Ohio | 30 | ||||
| 10/5/2024 | Bowling Green | 27 | at | Akron | 20 | |||
| Western Michigan | 45 | at | Ball State | 42 | ||||
| Massachusetts | 20 | at | Northern Illinois | 34 | Ind | |||
| Miami-Ohio | 20 | at | Toledo | 30 | ||||
| 10/12/2024 | Northern Illinois | 17 | at | Bowling Green | 7 | |||
| Toledo | 15 | at | Buffalo | 30 | ||||
| Ohio | 27 | at | Central Michigan | 25 | ||||
| Miami-Ohio | 38 | at | Eastern Michigan | 14 | ||||
| Ball State | 37 | at | Kent State | 35 | ||||
| Akron | 24 | at | Western Michigan | 34 | ||||
| 10/19/2024 | Kent State | 6 | at | Bowling Green | 27 | |||
| Western Michigan | 48 | at | Buffalo | 41 | ||||
| Central Michigan | 34 | at | Eastern Michigan | 38 | ||||
| Ohio | 20 | at | Miami-Ohio | 30 | ||||
| Toledo | 13 | at | Northern Illinois | 6 | ||||
| Ball State | 14 | at | Vanderbilt | 24 | @ SEC | |||
| 10/26/2024 | Eastern Michigan | 21 | at | Akron | 25 | |||
| Northern Illinois | 23 | at | Ball State | 25 | ||||
| Central Michigan | 7 | at | Miami-Ohio | 46 | ||||
| Buffalo | 16 | at | Ohio | 47 | ||||
| Bowling Green | 41 | at | Toledo | 26 | ||||
| Kent State | 21 | at | Western Michigan | 52 | ||||
| 11/2/2024 | Buffalo | 41 | at | Akron | 30 | |||
| Toledo | 29 | at | Eastern Michigan | 28 | ||||
| 11/5/2024 | Miami-Ohio | 27 | at | Ball State | 21 | |||
| Bowling Green | 23 | at | Central Michigan | 13 | ||||
| 11/6/2024 | Ohio | 41 | at | Kent State | 0 | |||
| Northern Illinois | 42 | at | Western Michigan | 28 | ||||
| 11/12/2024 | Western Michigan | 13 | at | Bowling Green | 31 | |||
| Ball State | 48 | at | Buffalo | 51 | OT | |||
| Central Michigan | 10 | at | Toledo | 37 | ||||
| 11/13/2024 | Kent State | 7 | at | Miami-Ohio | 34 | |||
| Akron | 16 | at | Northern Illinois | 29 | ||||
| Eastern Michigan | 10 | at | Ohio | 35 | ||||
| 11/19/2024 | Western Michigan | 14 | at | Central Michigan | 16 | |||
| Akron | 38 | at | Kent State | 17 | ||||
| Northern Illinois | 9 | at | Miami-Ohio | 20 | ||||
| 11/20/2024 | Buffalo | 37 | at | Eastern Michigan | 20 | |||
| Ohio | 24 | at | Toledo | 7 | ||||
| 11/23/2024 | Bowling Green | 38 | at | Ball State | 13 | |||
| 11/26/2024 | Toledo | 14 | at | Akron | 21 | OT | ||
| Kent State | 7 | at | Buffalo | 43 | ||||
| 11/29/2024 | Miami-Ohio | 28 | at | Bowling Green | 12 | |||
| Ball State | 21 | at | Ohio | 42 | ||||
| 11/30/2024 | Central Michigan | 16 | at | Northern Illinois | 24 | |||
| Eastern Michigan | 18 | at | Western Michigan | 26 | ||||
| 12/7/2024 | Ohio | 38 | vs | Miami-Ohio | 3 | MAC Championship - Detroit MI | ||
| 12/14/2024 | South Alabama | 30 | vs | Western Michigan | 23 | Salute to Veterans Bowl - Montgomery AL | vs SBC | |
| 12/20/2024 | Ohio | 30 | vs | Jacksonville State | 27 | Cure Bowl - Orlando FL | vs CUSA | |
| 12/23/2024 | Northern Illinois | vs | Fresno State | Famous Idaho Potato Bowl - Boise ID | vs MW | |||
| 12/26/2024 | Arkansas State | vs | Bowling Green | 68 Ventures Bowl - Mobile AL | vs SBC | |||
| Pittsburgh | vs | Toledo | GameAbove Sports Bowl - Detroit MI | vs ACC | ||||
| 12/28/2024 | Miami-Ohio | vs | Colorado State | Arizona Bowl - Tucson AZ | vs MW | |||
| 1/4/2025 | Buffalo | vs | Liberty | Bahamas Bowl - Nassau | vs CUSA |