| 9/2/2023 | Ohio State | 23 | at | Indiana (3-9,1-8) | 3 | |||
| 9/9/2023 | Youngstown State (8-5) | 7 | at | Ohio State | 35 | MVC (1AA) | ||
| 9/16/2023 | Western Kentucky (8-5) | 10 | at | Ohio State | 63 | CUSA | ||
| 9/23/2023 | Ohio State | 17 | at | Notre Dame (10-3) | 14 | at ND | ||
| 10/7/2023 | Maryland (8-5,4-5) | 17 | at | Ohio State | 37 | |||
| 10/14/2023 | Ohio State | 41 | at | Purdue (4-8,3-6) | 7 | |||
| 10/21/2023 | Penn State (10-3,7-2) | 12 | at | Ohio State | 20 | |||
| 10/28/2023 | Ohio State | 24 | at | Wisconsin (7-6,5-4) | 10 | |||
| 11/4/2023 | Ohio State | 35 | at | Rutgers (7-6,3-6) | 16 | |||
| 11/11/2023 | Michigan State (4-8,2-7) | 3 | at | Ohio State | 38 | |||
| 11/18/2023 | Minnesota (6-7,3-6) | 3 | at | Ohio State | 37 | |||
| 11/25/2023 | Ohio State | 24 | at | Michigan (15-0,10-0) | 30 | |||
| 12/29/2023 | Missouri (11-2) | 14 | vs | Ohio State | 3 | Cotton Bowl - Arlington TX | SEC |
| vs Ohio State | vs Other Opponents | Ohio State compared to OOs | |
| Record: | 2-11 | 99-56 | |
| Points Scored: | 11.23 | 29.78 | 18.55 |
| Points Allowed: | 30.54 | 21.65 | 8.89 |
| Margin: | -19.31 | 8.13 | 27.44 |
| Total Points: | 41.77 | 51.43 | -9.66 |