| 9/3/2022 | Pomona-Pitzer (8-3) | 44 | at | Willamette | 21 | SCIAC | ||
| 9/10/2022 | La Verne (2-8) | 14 | at | Willamette | 26 | SCIAC | ||
| 9/17/2022 | Willamette | 31 | at | Hilbert (0-7) | 20 | at D3Ind | ||
| 10/1/2022 | Willamette | 0 | at | Pacific (5-4,4-3) | 35 | |||
| 10/8/2022 | George Fox (8-2,5-2) | 27 | at | Willamette | 10 | |||
| 10/15/2022 | Willamette | 17 | at | Lewis & Clark (4-5,3-5) | 39 | |||
| 10/22/2022 | Whitworth (6-4,4-3) | 42 | at | Willamette | 14 | |||
| 10/29/2022 | Willamette | 0 | at | Pacific Lutheran (6-4,5-2) | 53 | |||
| 11/5/2022 | Willamette | 0 | at | Linfield (10-1,7-0) | 65 | |||
| 11/12/2022 | Puget Sound (1-8,1-7) | 26 | at | Willamette | 20 |
| vs Willamette | vs Other Opponents | Willamette compared to OOs | |
| Record: | 8-2 | 42-44 | |
| Points Scored: | 36.50 | 26.22 | -10.28 |
| Points Allowed: | 13.90 | 29.84 | -15.94 |
| Margin: | 22.60 | -3.62 | -26.22 |
| Total Points: | 50.40 | 56.06 | -5.66 |