| 9/17/2022 | Columbia | 38 | at | Marist (4-7) | 3 | at Pio | ||
| 9/24/2022 | Columbia | 42 | at | Georgetown (2-9) | 6 | at Pat | ||
| 10/1/2022 | Princeton (8-2,5-2) | 24 | at | Columbia | 6 | |||
| 10/8/2022 | Wagner (1-10) | 7 | at | Columbia | 28 | NE | ||
| 10/15/2022 | Columbia | 14 | at | Pennsylvania (8-2,5-2) | 34 | |||
| 10/22/2022 | Dartmouth (3-7,2-5) | 27 | at | Columbia | 24 | |||
| 10/28/2022 | Yale (8-2,6-1) | 41 | at | Columbia | 16 | |||
| 11/5/2022 | Columbia | 21 | at | Harvard (6-4,4-3) | 20 | |||
| 11/12/2022 | Columbia | 31 | at | Brown (3-7,1-6) | 24 | OT | ||
| 11/19/2022 | Cornell (5-5,2-5) | 22 | at | Columbia | 45 |
| vs Columbia | vs Other Opponents | Columbia compared to OOs | |
| Record: | 4-6 | 44-49 | |
| Points Scored: | 20.80 | 23.59 | 2.79 |
| Points Allowed: | 26.50 | 27.18 | -0.68 |
| Margin: | -5.70 | -3.59 | 2.11 |
| Total Points: | 47.30 | 50.77 | -3.47 |