| 9/4/2021 | Sewanee (0-10) | at | St Scholastica | Canceled COVID | SAA | |||
| 9/25/2021 | Augsburg (4-6,4-4) | 54 | at | St Scholastica | 14 | |||
| 10/2/2021 | St Scholastica | 18 | at | Hamline (4-6,2-6) | 34 | |||
| 10/9/2021 | Gustavus Adolphus (8-2,6-2) | 72 | at | St Scholastica | 7 | |||
| 10/16/2021 | Carleton (7-3,5-3) | 30 | at | St Scholastica | 14 | |||
| 10/23/2021 | St Scholastica | 14 | at | St Olaf (5-5,4-4) | 41 | |||
| 10/30/2021 | St Scholastica | 0 | at | St John's MN (11-1,8-0) | 81 | |||
| 11/6/2021 | Macalester (3-7,2-6) | 28 | at | St Scholastica | 14 | |||
| 11/13/2021 | St Scholastica | 20 | at | Hamline (4-6,2-6) | 21 |
| vs St Scholastica | vs Other Opponents | St Scholastica compared to OOs | |
| Record: | 8-0 | 36-46 | |
| Points Scored: | 45.13 | 26.79 | -18.34 |
| Points Allowed: | 12.63 | 32.16 | -19.53 |
| Margin: | 32.50 | -5.37 | -37.87 |
| Total Points: | 57.76 | 58.95 | -1.19 |