| 9/7/2019 | Greensboro | 8 | at | Apprentice | 23 | @ None (Unk?) | ||
| North Carolina Wesleyan | 31 | at | Emory & Henry | 24 | OT | @ ODC | ||
| Averett | 28 | at | Hampden-Sydney | 16 | @ ODC | |||
| Guilford | 43 | at | Huntingdon AL | 69 | ODC | |||
| Birmingham-Southern | 14 | at | LaGrange | 29 | SAA | |||
| Berry | 31 | at | Maryville | 10 | SAA | |||
| 9/14/2019 | Randolph-Macon | 30 | at | Averett | 27 | ODC | ||
| LaGrange | 9 | at | Berry | 34 | @ SAA | |||
| Huntingdon AL | 13 | at | Birmingham-Southern | 45 | @ SAA | |||
| Maryville | 22 | at | Centre | 27 | @ SAA | |||
| Ferrum | 55 | at | Greensboro | 7 | ODC | |||
| Guilford | 19 | at | Methodist | 14 | ODC | |||
| Shenandoah | 35 | at | North Carolina Wesleyan | 19 | ODC | |||
| 9/21/2019 | Christopher Newport | 6 | at | Brevard | 27 | NJAC | ||
| Averett | 35 | at | Ferrum | 12 | @ ODC | |||
| Hanover | 31 | at | Maryville | 10 | HCA | |||
| Catholic | 14 | at | Methodist | 30 | NEWMAC | |||
| Huntingdon AL | 14 | at | Wisconsin-Oshkosh | 44 | @ WIAC | |||
| 9/28/2019 | Brevard | 40 | at | Allen | 9 | @ NAIAInd (NAIA) | ||
| LaGrange | 50 | at | Apprentice | 13 | @ None (Unk?) | |||
| Greensboro | 27 | at | Gallaudet | 25 | @ ECFC | |||
| North Carolina Wesleyan | 21 | at | Stetson | 55 | @ Pio (1AA) | |||
| 10/5/2019 | Maryville | 10 | at | Brevard | 22 | |||
| Averett | 48 | at | Greensboro | 0 | ||||
| Methodist | 7 | at | Huntingdon AL | 48 | ||||
| North Carolina Wesleyan | 52 | at | LaGrange | 35 | ||||
| 10/12/2019 | LaGrange | 7 | at | Averett | 55 | |||
| Maryville | 35 | at | Huntingdon AL | 45 | ||||
| Brevard | 23 | at | Methodist | 24 | ||||
| Greensboro | 7 | at | North Carolina Wesleyan | 44 | ||||
| 10/19/2019 | North Carolina Wesleyan | 24 | at | Averett | 41 | |||
| Huntingdon AL | 21 | at | Brevard | 10 | ||||
| Greensboro | 23 | at | LaGrange | 40 | ||||
| Methodist | 13 | at | Maryville | 21 | ||||
| 10/26/2019 | Methodist | 41 | at | Greensboro | 10 | |||
| Averett | 35 | at | Huntingdon AL | 41 | ||||
| LaGrange | 10 | at | Maryville | 28 | ||||
| Brevard | 26 | at | North Carolina Wesleyan | 20 | ||||
| 11/2/2019 | Maryville | 13 | at | Averett | 31 | |||
| Huntingdon AL | 57 | at | Greensboro | 0 | ||||
| Brevard | 21 | at | LaGrange | 3 | ||||
| North Carolina Wesleyan | 48 | at | Methodist | 24 | ||||
| 11/9/2019 | Averett | 9 | at | Brevard | 10 | |||
| North Carolina Wesleyan | 23 | at | Huntingdon AL | 7 | ||||
| Greensboro | 7 | at | Maryville | 28 | ||||
| LaGrange | 33 | at | Methodist | 37 | ||||
| 11/16/2019 | Methodist | 7 | at | Averett | 43 | |||
| Brevard | 42 | at | Greensboro | 3 | ||||
| Huntingdon AL | 45 | at | LaGrange | 21 | ||||
| Maryville | 0 | at | North Carolina Wesleyan | 23 | ||||
| 11/23/2019 | Huntingdon AL | 27 | at | Berry | 24 | D3 Playoff round 1 | @ SAA | |
| Brevard | 42 | at | Carnegie Mellon | 28 | @ TPAC | |||
| Methodist | 35 | at | Shenandoah | 70 | @ ODC | |||
| 11/30/2019 | Huntingdon AL | 6 | at | Mary Hardin-Baylor | 42 | D3 Playoff round 2 | @ ASWC |