| 8/29/2019 | Pikeville (6-5) | 20 | at | Murray State | 59 | MSC (NAIA) | ||
| 9/7/2019 | Murray State | 17 | at | Georgia (12-2) | 63 | at SEC | ||
| 9/14/2019 | Murray State | 0 | at | Toledo (6-6) | 45 | at MAC | ||
| 9/21/2019 | Morehead State (5-7) | 7 | at | Murray State | 59 | Pio | ||
| 9/28/2019 | Murray State | 7 | at | Tennessee-Martin (7-5,6-2) | 40 | |||
| 10/5/2019 | Eastern Illinois (1-11,1-7) | 17 | at | Murray State | 24 | |||
| 10/12/2019 | Murray State | 31 | at | Tennessee State (3-9,2-6) | 17 | |||
| 10/19/2019 | Eastern Kentucky (7-5,5-3) | 34 | at | Murray State | 27 | |||
| 10/26/2019 | Murray State | 12 | at | Jacksonville State (6-6,3-5) | 14 | |||
| 11/2/2019 | Tennessee Tech (6-6,3-5) | 17 | at | Murray State | 7 | |||
| 11/16/2019 | Austin Peay (11-4,7-1) | 42 | at | Murray State | 7 | |||
| 11/23/2019 | Murray State | 24 | at | SE Missouri State (9-4,7-1) | 31 |
| vs Murray State | vs Other Opponents | Murray State compared to OOs | |
| Record: | 8-4 | 71-66 | |
| Points Scored: | 28.92 | 27.46 | -1.46 |
| Points Allowed: | 22.83 | 27.28 | -4.45 |
| Margin: | 6.09 | 0.18 | -5.91 |
| Total Points: | 51.75 | 54.74 | -2.99 |