| 8/31/2019 | Southern (8-5) | 28 | at | McNeese State | 34 | SWAC | ||
| 9/7/2019 | McNeese State | 14 | at | Oklahoma State (8-5) | 56 | at B12 | ||
| 9/14/2019 | Alcorn State (9-4) | 14 | at | McNeese State | 17 | SWAC | ||
| 9/21/2019 | McNeese State | 10 | at | Abilene Christian (5-7,4-5) | 17 | |||
| 9/28/2019 | Sam Houston (7-5,6-3) | 28 | at | McNeese State | 17 | |||
| 10/5/2019 | Southeastern Louisiana (8-5,6-3) | 34 | at | McNeese State | 38 | |||
| 10/12/2019 | McNeese State | 31 | at | Central Arkansas (9-4,7-2) | 40 | |||
| 10/19/2019 | Houston Baptist (5-7,2-6) | 27 | at | McNeese State | 42 | |||
| 10/26/2019 | McNeese State | 33 | at | Stephen F. Austin (3-9,3-6) | 10 | |||
| 11/2/2019 | Northwestern State (3-9,3-6) | 20 | at | McNeese State | 30 | |||
| 11/16/2019 | McNeese State | 20 | at | Nicholls State (9-5,7-2) | 34 | |||
| 11/23/2019 | McNeese State | 27 | at | Lamar (4-8,2-7) | 3 |
| vs McNeese State | vs Other Opponents | McNeese State compared to OOs | |
| Record: | 5-7 | 73-66 | |
| Points Scored: | 25.92 | 30.27 | 4.35 |
| Points Allowed: | 26.08 | 28.99 | -2.91 |
| Margin: | -0.16 | 1.28 | 1.44 |
| Total Points: | 52.00 | 59.26 | -7.26 |