| 8/31/2019 | Nicholls State | 14 | at | Kansas State (8-5) | 49 | at B12 | ||
| 9/14/2019 | Nicholls State | 42 | at | Prairie View (6-5) | 35 | at SWAC | ||
| 9/21/2019 | Nicholls State | 48 | at | Stephen F. Austin (3-9,3-6) | 30 | |||
| 9/28/2019 | Nicholls State | 3 | at | Texas State (3-9) | 24 | at SBC | ||
| 10/5/2019 | Central Arkansas (9-4,7-2) | 14 | at | Nicholls State | 34 | |||
| 10/12/2019 | Northwestern State (3-9,3-6) | 35 | at | Nicholls State | 45 | |||
| 10/19/2019 | Nicholls State | 0 | at | Sam Houston (7-5,6-3) | 17 | |||
| 10/26/2019 | Abilene Christian (5-7,4-5) | 37 | at | Nicholls State | 31 | OT | ||
| 11/2/2019 | Nicholls State | 27 | at | Incarnate Word (5-7,4-5) | 23 | |||
| 11/9/2019 | Houston Baptist (5-7,2-6) | 27 | at | Nicholls State | 48 | |||
| 11/16/2019 | McNeese State (7-5,5-4) | 20 | at | Nicholls State | 34 | |||
| 11/21/2019 | Nicholls State | 28 | at | Southeastern Louisiana (8-5,6-3) | 27 | |||
| 11/30/2019 | North Dakota (7-5) | 6 | at | Nicholls State | 24 | 1AA Playoffs Round 1 | BSky | |
| 12/7/2019 | Nicholls State | 13 | at | North Dakota State (16-0) | 37 | 1AA Playoff Round 2 | at MVC |
| vs Nicholls State | vs Other Opponents | Nicholls State compared to OOs | |
| Record: | 5-9 | 87-73 | |
| Points Scored: | 27.21 | 29.87 | 2.66 |
| Points Allowed: | 27.93 | 27.79 | 0.14 |
| Margin: | -0.72 | 2.08 | 2.80 |
| Total Points: | 55.14 | 57.66 | -2.52 |