| 9/1/2018 | Maryville | 3 | at | Berry (10-2) | 38 | at SAA | ||
| 9/8/2018 | Centre (10-2) | 40 | at | Maryville | 6 | SAA | ||
| 9/15/2018 | Maryville | at | Washington and Lee (5-4) | CCD | at ODC | |||
| 9/20/2018 | Maryville | at | Washington and Lee (5-4) | CCD | at ODC | |||
| 9/29/2018 | Brevard (4-6,3-4) | 3 | at | Maryville | 29 | |||
| 10/6/2018 | Huntingdon AL (4-5,4-3) | 13 | at | Maryville | 42 | |||
| 10/13/2018 | Maryville | 34 | at | Methodist (2-7,2-5) | 9 | |||
| 10/20/2018 | Maryville | 37 | at | LaGrange (3-7,2-5) | 17 | |||
| 10/27/2018 | Averett (8-2,6-1) | 0 | at | Maryville | 14 | |||
| 11/3/2018 | Maryville | 42 | at | Greensboro (1-9,0-7) | 7 | |||
| 11/10/2018 | North Carolina Wesleyan (5-5,4-3) | 14 | at | Maryville | 31 | |||
| 11/17/2018 | Maryville | 0 | at | Berry (10-2) | 31 | D3 Playooff Round 1 | at SAA |
| vs Maryville | vs Other Opponents | Maryville compared to OOs | |
| Record: | 3-7 | 62-48 | |
| Points Scored: | 17.20 | 30.09 | 12.89 |
| Points Allowed: | 23.80 | 26.85 | -3.05 |
| Margin: | -6.60 | 3.24 | 9.84 |
| Total Points: | 41.00 | 56.94 | -15.94 |