| 8/30/2018 | LaGrange (3-7) | 28 | at | Birmingham-Southern | 34 | USASC | ||
| 9/8/2018 | Birmingham-Southern | 41 | at | Huntingdon AL (4-5) | 35 | at USASC | ||
| 9/22/2018 | Rhodes (5-5,3-5) | 29 | at | Birmingham-Southern | 10 | |||
| 9/29/2018 | Birmingham-Southern | 17 | at | Trinity TX (7-3,6-2) | 24 | |||
| 10/6/2018 | Hendrix (2-8,1-7) | 41 | at | Birmingham-Southern | 57 | |||
| 10/13/2018 | Birmingham-Southern | 13 | at | Sewanee (4-6,3-5) | 10 | |||
| 10/20/2018 | Austin (2-8,2-6) | 35 | at | Birmingham-Southern | 47 | |||
| 10/27/2018 | Birmingham-Southern | 10 | at | Berry (10-2,7-1) | 26 | |||
| 11/3/2018 | Birmingham-Southern | 34 | at | Millsaps (5-5,3-5) | 17 | |||
| 11/10/2018 | Centre (10-2,7-1) | 56 | at | Birmingham-Southern | 20 |
| vs Birmingham-Southern | vs Other Opponents | Birmingham-Southern compared to OOs | |
| Record: | 4-6 | 48-45 | |
| Points Scored: | 30.10 | 26.92 | -3.18 |
| Points Allowed: | 28.30 | 24.68 | 3.62 |
| Margin: | 1.80 | 2.24 | 0.44 |
| Total Points: | 58.40 | 51.60 | 6.80 |