| 8/30/2018 | Carson-Newman (7-4) | 9 | at | West Florida | 19 | SAC | ||
| 9/8/2018 | West Florida | 17 | at | Midwestern State (8-2) | 38 | at LSC | ||
| 9/15/2018 | Shorter (0-11,0-8) | 7 | at | West Florida | 51 | |||
| 9/22/2018 | West Florida | 34 | at | Mississippi College (3-7,1-6) | 21 | |||
| 9/29/2018 | West Florida | 30 | at | Delta State (2-8,2-6) | 21 | |||
| 10/6/2018 | West Florida | 24 | at | North Alabama (7-3) | 19 | at Ind1AA | ||
| 10/13/2018 | West Georgia (10-2,7-1) | 27 | at | West Florida | 7 | |||
| 10/20/2018 | Florida Tech (8-4,5-3) | 30 | at | West Florida | 28 | |||
| 10/27/2018 | West Florida | 26 | at | North Greenville (4-6,3-4) | 10 | |||
| 11/3/2018 | Valdosta State (14-0,8-0) | 48 | at | West Florida | 21 | |||
| 11/10/2018 | West Florida | 7 | at | West Alabama (8-4,5-3) | 45 |
| vs West Florida | vs Other Opponents | West Florida compared to OOs | |
| Record: | 5-6 | 66-45 | |
| Points Scored: | 25.00 | 30.75 | 5.75 |
| Points Allowed: | 24.00 | 27.42 | -3.42 |
| Margin: | 1.00 | 3.33 | 2.33 |
| Total Points: | 49.00 | 58.17 | -9.17 |