| 8/30/2018 | Southwest Minnesota State | 13 | at | Minnesota State-Mankato (13-1,11-0) | 49 | | | |
| 9/8/2018 | Wayne State NE (3-8,3-8) | 23 | at | Southwest Minnesota State | 14 | | | |
| 9/15/2018 | Southwest Minnesota State | 21 | at | Sioux Falls (7-4,7-4) | 39 | | | |
| 9/22/2018 | Upper Iowa (3-8,3-8) | 20 | at | Southwest Minnesota State | 21 | | | |
| 9/29/2018 | Southwest Minnesota State | 54 | at | Mary (1-10,1-10) | 24 | | | |
| 10/6/2018 | Minnesota-Crookston (1-10,1-10) | 6 | at | Southwest Minnesota State | 55 | | | |
| 10/13/2018 | Southwest Minnesota State | 13 | at | Minnesota-Duluth (11-1,11-0) | 42 | | | |
| 10/20/2018 | Northern State (4-7,4-7) | 7 | at | Southwest Minnesota State | 35 | | | |
| 10/27/2018 | Southwest Minnesota State | 26 | at | Winona State (8-3,8-3) | 38 | | | |
| 11/3/2018 | Concordia-St Paul (5-6,5-6) | 16 | at | Southwest Minnesota State | 10 | | | |
| 11/10/2018 | Augustana SD (7-4,7-4) | 28 | at | Southwest Minnesota State | 18 | | | |