| 9/8/2018 | Prairie View (5-6) | 32 | at | Sam Houston | 41 | SWAC | ||
| 9/15/2018 | North Dakota (6-5) | 24 | at | Sam Houston | 23 | Ind1AA | ||
| 9/22/2018 | Sam Houston | 7 | at | Nicholls State (9-4,7-2) | 27 | |||
| 9/29/2018 | Central Arkansas (6-5,5-4) | 31 | at | Sam Houston | 34 | OT | ||
| 10/6/2018 | Stephen F. Austin (2-8,2-7) | 21 | vs | Sam Houston | 54 | Houston TX | ||
| 10/13/2018 | Sam Houston | 42 | at | Northwestern State (5-6,4-5) | 28 | |||
| 10/20/2018 | Sam Houston | 23 | at | Lamar (7-5,6-3) | 41 | |||
| 10/27/2018 | Southeastern Louisiana (4-7,4-5) | 25 | at | Sam Houston | 28 | |||
| 11/3/2018 | Sam Houston | 26 | at | Incarnate Word (6-5,6-2) | 43 | |||
| 11/10/2018 | Abilene Christian (6-5,5-4) | 17 | at | Sam Houston | 10 | |||
| 11/17/2018 | Sam Houston | 42 | at | Houston Baptist (1-10,0-9) | 20 |
| vs Sam Houston | vs Other Opponents | Sam Houston compared to OOs | |
| Record: | 5-6 | 52-60 | |
| Points Scored: | 28.09 | 28.95 | 0.86 |
| Points Allowed: | 30.00 | 30.01 | -0.01 |
| Margin: | -1.91 | -1.06 | 0.85 |
| Total Points: | 58.09 | 58.96 | -0.87 |