| 9/1/2018 | Mississippi | 47 | vs | Texas Tech (5-7) | 27 | Houston TX | vs B12 | |
| 9/8/2018 | Southern Illinois (2-9) | 41 | at | Mississippi | 76 | MVC (1AA) | ||
| 9/15/2018 | Alabama (14-1,9-0) | 62 | at | Mississippi | 7 | |||
| 9/22/2018 | Kent State (2-10) | 17 | at | Mississippi | 38 | MAC | ||
| 9/29/2018 | Mississippi | 16 | at | LSU (10-3,5-3) | 45 | |||
| 10/6/2018 | UL Monroe (6-6) | 21 | at | Mississippi | 70 | SBC | ||
| 10/13/2018 | Mississippi | 37 | vs | Arkansas (2-10,0-8) | 33 | Little Rock AR | ||
| 10/20/2018 | Auburn (8-5,3-5) | 31 | at | Mississippi | 16 | |||
| 11/3/2018 | South Carolina (7-6,4-4) | 48 | at | Mississippi | 44 | |||
| 11/10/2018 | Mississippi | 24 | at | Texas A&M (9-4,5-3) | 38 | |||
| 11/17/2018 | Mississippi | 29 | at | Vanderbilt (6-7,3-5) | 36 | |||
| 11/22/2018 | Mississippi State (8-5,4-4) | 35 | at | Mississippi | 3 |
| vs Mississippi | vs Other Opponents | Mississippi compared to OOs | |
| Record: | 7-5 | 72-68 | |
| Points Scored: | 36.17 | 30.84 | -5.33 |
| Points Allowed: | 33.92 | 26.11 | 7.81 |
| Margin: | 2.25 | 4.73 | 2.48 |
| Total Points: | 70.09 | 56.95 | 13.14 |