| 8/31/2018 | Worcester Polytechnic | 54 | at | Anna Maria | 0 | NEWMAC | ||
| Dean | 41 | at | Curry | 44 | @ CCF | |||
| 9/1/2018 | UMass Dartmouth | 49 | at | Alfred State | 21 | MSCAC | ||
| Gallaudet | 21 | at | Alvernia | 26 | @ MidAC | |||
| Plymouth State | 38 | at | Castleton State | 0 | MSCAC | |||
| SUNY-Maritime | 36 | at | Maine Maritime | 8 | @ NEWMAC | |||
| Husson | 7 | at | Union NY | 30 | @ LL | |||
| 9/7/2018 | Anna Maria | 14 | at | Nichols | 35 | @ CCF | ||
| Massachusetts Maritime | 21 | at | SUNY-Maritime | 51 | MSCAC | |||
| 9/8/2018 | Western Connecticut | 33 | at | Dean | 22 | MSCAC | ||
| Castleton State | 34 | at | Fitchburg State | 13 | @ MSCAC | |||
| Gallaudet | 28 | at | Greensboro | 44 | @ USASC | |||
| Alfred State | 24 | at | Hartwick | 49 | @ E8 | |||
| Husson | 47 | at | University of New England | 7 | @ CCF | |||
| 9/14/2018 | Merchant Marine | 34 | at | SUNY-Maritime | 21 | NEWMAC | ||
| 9/15/2018 | Rochester | 20 | at | Alfred State | 14 | LL | ||
| Anna Maria | 7 | at | Curry | 41 | @ CCF | |||
| Apprentice | vs | Gallaudet | CCD | vs D3Ind | ||||
| Western New England | 31 | at | Husson | 28 | CCF | |||
| Castleton State | 0 | at | Norwich | 40 | @ NEWMAC | |||
| Dean | 18 | at | Salve Regina | 27 | @ CCF | |||
| 9/22/2018 | Dean | 42 | at | Becker | 15 | @ CCF | ||
| Alfred State | 7 | at | Nichols | 43 | @ CCF | |||
| Anna Maria | 7 | at | Western New England | 59 | @ CCF | |||
| 9/29/2018 | Gallaudet | 29 | at | Anna Maria | 9 | |||
| Alfred State | 26 | at | Dean | 44 | ||||
| Castleton State | 33 | at | Misericordia | 52 | @ MidAC | |||
| Husson | 35 | at | SUNY-Maritime | 21 | ||||
| 10/5/2018 | Dean | 16 | at | Husson | 48 | |||
| 10/6/2018 | SUNY-Maritime | 55 | at | Alfred State | 14 | |||
| Anna Maria | 31 | at | Castleton State | 24 | ||||
| 10/13/2018 | Husson | 56 | at | Alfred State | 14 | |||
| Castleton State | 25 | at | Gallaudet | 35 | ||||
| Dean | 7 | at | SUNY-Maritime | 35 | ||||
| 10/20/2018 | SUNY-Maritime | 68 | at | Castleton State | 41 | |||
| Gallaudet | 21 | at | Dean | 53 | ||||
| Anna Maria | 14 | at | Husson | 54 | ||||
| 10/27/2018 | SUNY-Maritime | 14 | at | Anna Maria | 7 | |||
| Husson | 48 | at | Castleton State | 0 | ||||
| Alfred State | 9 | at | Gallaudet | 13 | ||||
| 11/3/2018 | Anna Maria | 28 | at | Alfred State | 30 | |||
| Castleton State | 17 | at | Dean | 19 | ||||
| Gallaudet | 2 | at | Husson | 63 | ||||
| Hampton | 51 | at | SUNY-Maritime | 10 | Ind1AA (1AA) | |||
| 11/10/2018 | Alfred State | 3 | at | Castleton State | 21 | |||
| Anna Maria | 13 | at | Dean | 19 | ||||
| SUNY-Maritime | 34 | at | Gallaudet | 7 | ||||
| Husson | 21 | at | Plymouth State | 10 | @ MSCAC | |||
| 11/17/2018 | Husson | 14 | at | Rensselaer | 38 | D3 Playooff Round 1 | @ LL | |
| SUNY-Maritime | 14 | at | Springfield | 17 | @ NEWMAC |