| 9/1/2018 | Rochester | 10 | at | Case Western Reserve (8-2) | 38 | at TPAC | ||
| 9/8/2018 | Carnegie Mellon (6-4) | 31 | at | Rochester | 7 | TPAC | ||
| 9/15/2018 | Rochester | 20 | at | Alfred State (1-9) | 14 | at ECFC | ||
| 9/22/2018 | Emory & Henry (4-5) | 52 | at | Rochester | 17 | ODC | ||
| 10/6/2018 | St Lawrence (2-8,1-4) | 38 | at | Rochester | 24 | |||
| 10/13/2018 | Rochester | 7 | at | Hobart (5-4,3-2) | 52 | |||
| 10/20/2018 | Rochester | 3 | at | Ithaca (8-3,4-1) | 28 | |||
| 10/27/2018 | Rensselaer (10-2,4-1) | 42 | at | Rochester | 0 | |||
| 11/3/2018 | Rochester | 14 | at | Union NY (7-2,3-2) | 35 | |||
| 11/10/2018 | Alfred (7-4) | 41 | at | Rochester | 13 | E8 |
| vs Rochester | vs Other Opponents | Rochester compared to OOs | |
| Record: | 9-1 | 49-42 | |
| Points Scored: | 37.10 | 26.78 | -10.32 |
| Points Allowed: | 11.50 | 25.30 | -13.80 |
| Margin: | 25.60 | 1.48 | -24.12 |
| Total Points: | 48.60 | 52.08 | -3.48 |