| 9/1/2018 | Merchant Marine (8-2) | 30 | at | Misericordia | 9 | NEWMAC | ||
| 9/15/2018 | Widener (4-6,4-5) | 35 | at | Misericordia | 36 | |||
| 9/22/2018 | Misericordia | 47 | at | Wilkes (5-5,5-4) | 45 | |||
| 9/29/2018 | Castleton State (2-8) | 33 | at | Misericordia | 52 | ECFC | ||
| 10/6/2018 | Alvernia (1-9,0-8) | 33 | at | Misericordia | 45 | |||
| 10/13/2018 | Misericordia | 25 | at | Lebanon Valley (2-8,2-7) | 21 | |||
| 10/20/2018 | Fairleigh Dickinson-Florham (6-4,4-4) | 33 | at | Misericordia | 37 | |||
| 10/27/2018 | Misericordia | 41 | at | King's (5-5,4-4) | 23 | |||
| 11/3/2018 | Misericordia | 39 | at | Albright (0-10,0-8) | 29 | |||
| 11/10/2018 | Lycoming (5-6,5-4) | 21 | at | Misericordia | 14 | |||
| 11/17/2018 | Ursinus (8-3) | 70 | at | Misericordia | 14 | Cen |
| vs Misericordia | vs Other Opponents | Misericordia compared to OOs | |
| Record: | 3-8 | 43-58 | |
| Points Scored: | 33.91 | 23.84 | -10.07 |
| Points Allowed: | 32.64 | 28.98 | 3.66 |
| Margin: | 1.27 | -5.14 | -6.41 |
| Total Points: | 66.55 | 52.82 | 13.73 |