| 9/2/2017 | Temple | 16 | at | Notre Dame | 49 | AAC | ||
| 9/9/2017 | Georgia | 20 | at | Notre Dame | 19 | SEC | ||
| 9/16/2017 | Notre Dame | 49 | at | Boston College | 20 | @ ACC | ||
| 9/23/2017 | Notre Dame | 38 | at | Michigan State | 18 | @ B10 | ||
| 9/30/2017 | Miami-Ohio | 17 | at | Notre Dame | 52 | MAC | ||
| 10/7/2017 | Notre Dame | 33 | at | North Carolina | 10 | @ ACC | ||
| 10/21/2017 | Southern California | 14 | at | Notre Dame | 49 | P12 | ||
| 10/28/2017 | North Carolina State | 14 | at | Notre Dame | 35 | ACC | ||
| 11/4/2017 | Wake Forest | 37 | at | Notre Dame | 48 | ACC | ||
| 11/11/2017 | Notre Dame | 8 | at | Miami-Florida | 41 | @ ACC | ||
| 11/18/2017 | Navy | 17 | at | Notre Dame | 24 | AAC | ||
| 11/25/2017 | Notre Dame | 20 | at | Stanford | 38 | @ P12 | ||
| 1/1/2018 | Notre Dame | 21 | vs | LSU | 17 | Citrus Bowl (Orlanda FL) | vs SEC |