| 8/26/2017 | Missouri Baptist | 7 | at | Lyon | 28 | @ CSFL | ||
| Kansas Wesleyan | 24 | at | Olivet Nazarene | 31 | KCAC | |||
| Bacone | 7 | at | Robert Morris IL | 22 | CSFL | |||
| Morningside | 41 | at | St Francis IL | 24 | GPAC | |||
| 8/31/2017 | Concordia MI | 25 | at | Davenport | 6 | @ GLIAC (D2) | ||
| Marian IN | 27 | at | St Xavier | 32 | ||||
| 9/2/2017 | St Francis IN | 55 | at | Jamestown | 7 | @ NSAA | ||
| Olivet Nazarene | 39 | at | Lindenwood-Belleville | 14 | ||||
| Robert Morris IL | 31 | at | North Central | 33 | @ CCIW (D3) | |||
| Northwood | 38 | at | Siena Heights | 7 | GLIAC (D2) | |||
| Dakota State | 24 | at | Saint Ambrose | 27 | NSAA | |||
| Malone | 21 | at | Taylor | 28 | GMAC (D2) | |||
| Trinity International | 58 | at | Wisconsin Lutheran | 21 | @ NAC (D3) | |||
| 9/9/2017 | Robert Morris IL | 28 | at | Marian IN | 49 | |||
| St Xavier | 48 | at | Missouri Baptist | 13 | ||||
| Olivet Nazarene | 20 | at | Siena Heights | 11 | ||||
| Lindenwood-Belleville | 14 | at | Saint Ambrose | 52 | ||||
| St Francis IL | 23 | at | St Francis IN | 68 | ||||
| Concordia MI | 34 | at | Trinity International | 20 | ||||
| 9/16/2017 | Taylor | 21 | at | Butler | 27 | @ Pio (1AA) | ||
| Wisconsin-River Falls | 30 | at | Missouri Baptist | 3 | WIAC (D3) | |||
| Concordia MI | 38 | at | Olivet Nazarene | 16 | ||||
| Siena Heights | 31 | at | Robert Morris IL | 29 | ||||
| St Francis IN | 49 | at | Saint Ambrose | 21 | ||||
| Lindenwood-Belleville | 0 | at | St Xavier | 45 | ||||
| Valparaiso | 44 | at | Trinity International | 10 | Pio (1AA) | |||
| 9/23/2017 | Robert Morris IL | 26 | at | Concordia MI | 34 | |||
| Saint Ambrose | 37 | at | Missouri Baptist | 42 | ||||
| Marian IN | 40 | at | Olivet Nazarene | 21 | ||||
| St Francis IL | 16 | at | Siena Heights | 34 | ||||
| St Xavier | 23 | at | St Francis IN | 48 | ||||
| Trinity International | 19 | at | Taylor | 33 | ||||
| 9/30/2017 | Lindenwood-Belleville | 0 | at | Concordia MI | 65 | |||
| St Francis IN | 31 | at | Marian IN | 24 | ||||
| Trinity International | 41 | at | Olivet Nazarene | 44 | ||||
| Robert Morris IL | 17 | at | Quincy | 31 | @ GLV (D2) | |||
| Missouri Baptist | 0 | at | Siena Heights | 30 | ||||
| St Francis IL | 42 | at | Saint Ambrose | 19 | ||||
| Taylor | 20 | at | St Xavier | 24 | ||||
| 10/7/2017 | Missouri Baptist | 50 | at | Lindenwood-Belleville | 16 | |||
| Saint Ambrose | 24 | at | Marian IN | 61 | ||||
| Missouri S&T | 52 | at | St Francis IL | 30 | GLV (D2) | |||
| Concordia MI | 18 | at | St Francis IN | 35 | ||||
| Siena Heights | 48 | at | Taylor | 26 | ||||
| 10/14/2017 | St Francis IL | 48 | at | Lindenwood-Belleville | 6 | |||
| Taylor | 14 | at | Marian IN | 56 | ||||
| Concordia MI | 66 | at | Missouri Baptist | 21 | ||||
| Olivet Nazarene | at | Robert Morris IL | Postponed | |||||
| St Francis IN | 36 | at | Siena Heights | 9 | ||||
| Trinity International | 13 | at | St Xavier | 38 | ||||
| 10/15/2017 | Olivet Nazarene | 14 | at | Robert Morris IL | 21 | |||
| 10/21/2017 | Marian IN | 36 | at | Concordia MI | 39 | |||
| St Francis IN | 56 | at | Missouri Baptist | 23 | ||||
| Olivet Nazarene | 31 | at | St Francis IL | 43 | ||||
| Saint Ambrose | 28 | at | St Xavier | 41 | ||||
| Lindenwood-Belleville | 10 | at | Taylor | 63 | ||||
| Robert Morris IL | 28 | at | Trinity International | 34 | OT | |||
| 10/28/2017 | Taylor | 14 | at | Concordia MI | 31 | |||
| Siena Heights | 21 | at | Marian IN | 27 | ||||
| Trinity Bible | 6 | at | Olivet Nazarene | 49 | None (Unk?) | |||
| Robert Morris IL | 29 | at | Saint Ambrose | 35 | ||||
| St Xavier | 30 | at | St Francis IL | 28 | ||||
| Lindenwood-Belleville | 0 | at | St Francis IN | 70 | ||||
| Missouri Baptist | 34 | at | Trinity International | 27 | ||||
| 11/4/2017 | Siena Heights | 48 | at | Lindenwood-Belleville | 0 | |||
| Missouri Baptist | 0 | at | Marian IN | 62 | ||||
| St Francis IL | 28 | at | Robert Morris IL | 18 | ||||
| Taylor | 20 | at | St Francis IN | 40 | ||||
| Olivet Nazarene | 29 | at | St Xavier | 30 | 2OT | |||
| Saint Ambrose | 12 | at | Trinity International | 7 | ||||
| 11/11/2017 | Siena Heights | 0 | at | Concordia MI | 37 | |||
| Marian IN | 63 | at | Lindenwood-Belleville | 0 | ||||
| Saint Ambrose | 17 | at | Olivet Nazarene | 20 | ||||
| St Xavier | 31 | at | Robert Morris IL | 7 | ||||
| Trinity International | 30 | at | St Francis IL | 55 | ||||
| Missouri Baptist | 13 | at | Taylor | 21 | ||||
| 11/18/2017 | Concordia MI | 10 | at | Reinhardt | 39 | @ MSC | ||
| Benedictine KS | 21 | at | St Francis IN | 26 | HAAC | |||
| Grand View | 23 | at | St Xavier | 39 | HAAC | |||
| 11/25/2017 | St Xavier | 7 | at | Morningside | 52 | NAIA Quarterfinal | @ GPAC | |
| Northwestern IA | 3 | at | St Francis IN | 30 | NAIA Quarterfinal | GPAC | ||
| 12/2/2017 | Morningside | 36 | at | St Francis IN | 43 | NAIA Semifinal | GPAC | |
| 12/16/2017 | Reinhardt | 13 | vs | St Francis IN | 24 | NAIA Championship (Daytona Beach FL) | vs MSC |