| 9/2/2017 | West Florida (11-4) | 20 | at | Missouri S&T | 16 | GSC | ||
| 9/9/2017 | Northwood (7-4) | 47 | at | Missouri S&T | 34 | GLIAC | ||
| 9/16/2017 | Missouri S&T | 27 | at | Truman State (5-6,5-3) | 11 | |||
| 9/23/2017 | Missouri S&T | 48 | at | Malone (1-9) | 21 | at GMAC | ||
| 9/30/2017 | Missouri S&T | 27 | at | William Jewell (2-9,2-5) | 17 | |||
| 10/7/2017 | Missouri S&T | 52 | at | St Francis IL (5-5) | 30 | at MSFA | ||
| 10/14/2017 | Missouri S&T | 37 | at | Lincoln MO (1-9,0-7) | 3 | |||
| 10/21/2017 | McKendree (7-4,5-2) | 39 | at | Missouri S&T | 31 | |||
| 10/28/2017 | Southwest Baptist (5-5,4-4) | 38 | at | Missouri S&T | 41 | |||
| 11/4/2017 | Missouri S&T | 34 | at | Indianapolis (11-1,7-0) | 43 | |||
| 11/11/2017 | Quincy (3-8,1-6) | 16 | at | Missouri S&T | 63 |
| vs Missouri S&T | vs Other Opponents | Missouri S&T compared to OOs | |
| Record: | 4-7 | 54-57 | |
| Points Scored: | 25.91 | 25.06 | -0.85 |
| Points Allowed: | 37.27 | 26.80 | 10.47 |
| Margin: | -11.36 | -1.74 | 9.62 |
| Total Points: | 63.18 | 51.86 | 11.32 |