| 9/3/2016 | McDaniel | 21 | at | Catholic (3-7) | 28 | OT | at ODC | |
| 9/10/2016 | McDaniel | 27 | at | Moravian (5-5,4-5) | 55 | |||
| 9/17/2016 | Muhlenberg (9-2,8-1) | 42 | at | McDaniel | 13 | |||
| 9/24/2016 | Ursinus (2-8,2-7) | 27 | at | McDaniel | 30 | |||
| 10/1/2016 | McDaniel | 23 | at | Gettysburg (3-7,3-6) | 38 | |||
| 10/15/2016 | McDaniel | 7 | at | Franklin & Marshall (7-4,6-3) | 25 | |||
| 10/22/2016 | Dickinson (1-9,1-8) | 7 | at | McDaniel | 14 | |||
| 10/29/2016 | McDaniel | 20 | at | Juniata (4-6,3-6) | 13 | |||
| 11/5/2016 | Susquehanna (6-4,6-3) | 37 | at | McDaniel | 20 | |||
| 11/12/2016 | McDaniel | 28 | at | Johns Hopkins (11-1,9-0) | 48 |
| vs McDaniel | vs Other Opponents | McDaniel compared to OOs | |
| Record: | 7-3 | 44-50 | |
| Points Scored: | 32.00 | 28.67 | -3.33 |
| Points Allowed: | 20.30 | 30.13 | -9.83 |
| Margin: | 11.70 | -1.46 | -13.16 |
| Total Points: | 52.30 | 58.80 | -6.50 |