| 9/3/2016 | Lebanon Valley (4-6) | 6 | at | Franklin & Marshall | 30 | MidAC | ||
| 9/10/2016 | Franklin & Marshall | 19 | at | Muhlenberg (9-2,8-1) | 35 | |||
| 9/17/2016 | Ursinus (2-8,2-7) | 12 | at | Franklin & Marshall | 34 | |||
| 9/24/2016 | Franklin & Marshall | 45 | at | Juniata (4-6,3-6) | 22 | |||
| 10/1/2016 | Franklin & Marshall | 20 | at | Dickinson (1-9,1-8) | 10 | |||
| 10/15/2016 | McDaniel (3-7,3-6) | 7 | at | Franklin & Marshall | 25 | |||
| 10/22/2016 | Moravian (5-5,4-5) | 17 | at | Franklin & Marshall | 24 | |||
| 10/29/2016 | Franklin & Marshall | 10 | at | Susquehanna (6-4,6-3) | 20 | |||
| 11/5/2016 | Johns Hopkins (11-1,9-0) | 48 | at | Franklin & Marshall | 28 | |||
| 11/12/2016 | Franklin & Marshall | 28 | at | Gettysburg (3-7,3-6) | 21 | |||
| 11/19/2016 | Franklin & Marshall | 23 | at | Albright (8-3) | 28 | at MidAC |
| vs Franklin & Marshall | vs Other Opponents | Franklin & Marshall compared to OOs | |
| Record: | 4-7 | 52-51 | |
| Points Scored: | 20.55 | 29.60 | 9.05 |
| Points Allowed: | 26.00 | 28.66 | -2.66 |
| Margin: | -5.45 | 0.94 | 6.39 |
| Total Points: | 46.55 | 58.26 | -11.71 |