| 9/3/2016 | Juniata (4-6) | 31 | at | Grove City | 26 | Cen | ||
| 9/10/2016 | Grove City | 13 | at | Washington & Jefferson (9-2,7-2) | 65 | |||
| 9/17/2016 | Case Western Reserve (9-1,7-1) | 55 | at | Grove City | 0 | |||
| 9/24/2016 | Grove City | 32 | at | St Vincent (5-5,4-5) | 57 | |||
| 10/1/2016 | Waynesburg (2-8,2-7) | 14 | at | Grove City | 10 | |||
| 10/8/2016 | Grove City | 20 | at | Thomas More (9-2,8-0) | 70 | |||
| 10/15/2016 | Westminster PA (8-3,6-3) | 52 | at | Grove City | 23 | |||
| 10/29/2016 | Grove City | 14 | at | Geneva (3-7,3-6) | 21 | |||
| 11/5/2016 | Grove City | 14 | at | Bethany WV (3-7,2-7) | 33 | |||
| 11/12/2016 | Thiel (4-6,3-6) | 47 | at | Grove City | 41 |
| vs Grove City | vs Other Opponents | Grove City compared to OOs | |
| Record: | 10-0 | 46-47 | |
| Points Scored: | 44.50 | 28.26 | -16.24 |
| Points Allowed: | 19.30 | 28.02 | -8.72 |
| Margin: | 25.20 | 0.24 | -24.96 |
| Total Points: | 63.80 | 56.28 | 7.52 |