| 9/3/2016 | Washington U (8-3) | 41 | at | Carnegie Mellon | 34 | OT | SAA | |
| 9/17/2016 | Waynesburg (2-8,2-7) | 23 | at | Carnegie Mellon | 35 | |||
| 9/24/2016 | Carnegie Mellon | 16 | at | Thomas More (9-2,8-0) | 20 | |||
| 10/1/2016 | Bethany WV (3-7,2-7) | 26 | at | Carnegie Mellon | 49 | |||
| 10/8/2016 | Carnegie Mellon | 52 | at | Washington & Jefferson (9-2,7-2) | 55 | OT | ||
| 10/15/2016 | Carnegie Mellon | 29 | at | Geneva (3-7,3-6) | 10 | |||
| 10/22/2016 | Thiel (4-6,3-6) | 33 | at | Carnegie Mellon | 49 | |||
| 10/29/2016 | Westminster PA (8-3,6-3) | 23 | at | Carnegie Mellon | 35 | |||
| 11/5/2016 | Carnegie Mellon | 37 | at | Chicago (4-6) | 24 | at SAA | ||
| 11/12/2016 | Carnegie Mellon | 26 | at | Case Western Reserve (9-1,7-1) | 21 | |||
| 11/20/2016 | Salisbury (8-3) | 52 | vs | Carnegie Mellon | 20 | Philadelphia PA | NJAC |
| vs Carnegie Mellon | vs Other Opponents | Carnegie Mellon compared to OOs | |
| Record: | 4-7 | 63-41 | |
| Points Scored: | 29.82 | 31.62 | 1.80 |
| Points Allowed: | 34.73 | 25.33 | 9.40 |
| Margin: | -4.91 | 6.29 | 11.20 |
| Total Points: | 64.55 | 56.95 | 7.60 |