| 9/3/2016 | LaGrange (3-7) | 47 | at | Birmingham-Southern | 27 | USASC | ||
| 9/10/2016 | Birmingham-Southern | 28 | at | Huntingdon AL (9-2) | 49 | at USASC | ||
| 9/17/2016 | Birmingham-Southern | 21 | at | Sewanee (0-10,0-8) | 16 | |||
| 9/24/2016 | Washington U (8-3,7-1) | 36 | at | Birmingham-Southern | 21 | |||
| 10/1/2016 | Birmingham-Southern | 34 | at | Chicago (4-6,4-4) | 38 | |||
| 10/8/2016 | Hendrix (7-3,5-3) | 47 | at | Birmingham-Southern | 17 | |||
| 10/15/2016 | Birmingham-Southern | 28 | at | Millsaps (3-7,2-6) | 41 | |||
| 10/22/2016 | Rhodes (6-4,4-4) | 50 | at | Birmingham-Southern | 16 | |||
| 10/29/2016 | Centre (8-2,6-2) | 45 | at | Birmingham-Southern | 30 | |||
| 11/5/2016 | Birmingham-Southern | 12 | at | Berry (9-1,7-1) | 38 |
| vs Birmingham-Southern | vs Other Opponents | Birmingham-Southern compared to OOs | |
| Record: | 9-1 | 48-44 | |
| Points Scored: | 40.70 | 33.40 | -7.30 |
| Points Allowed: | 23.40 | 31.47 | -8.07 |
| Margin: | 17.30 | 1.93 | -15.37 |
| Total Points: | 64.10 | 64.87 | -0.77 |