| 9/1/2016 | Sioux Falls | 49 | at | Saint Cloud State (5-6,5-6) | 13 | | | |
| 9/10/2016 | Minnesota State-Moorhead (7-4,7-4) | 21 | at | Sioux Falls | 42 | | | |
| 9/17/2016 | Sioux Falls | 41 | at | Minot State (3-8,3-8) | 14 | | | |
| 9/24/2016 | Bemidji State (9-3,8-3) | 36 | at | Sioux Falls | 37 | | | |
| 10/1/2016 | Sioux Falls | 35 | at | Augustana SD (8-3,8-3) | 20 | | | |
| 10/8/2016 | Southwest Minnesota State (5-6,5-6) | 28 | at | Sioux Falls | 48 | | | |
| 10/15/2016 | Sioux Falls | 41 | at | Winona State (8-3,8-3) | 30 | | | |
| 10/22/2016 | Concordia-St Paul (2-9,2-9) | 17 | at | Sioux Falls | 51 | | | |
| 10/29/2016 | Sioux Falls | 24 | at | Minnesota State-Mankato (8-3,8-3) | 14 | | | |
| 11/5/2016 | Upper Iowa (3-8,3-8) | 7 | at | Sioux Falls | 51 | | | |
| 11/12/2016 | Wayne State NE (3-8,3-8) | 7 | at | Sioux Falls | 30 | | | |
| 11/19/2016 | Azusa Pacific (9-3) | 21 | at | Sioux Falls | 34 | | | GNWAC |
| 11/26/2016 | Harding (13-1) | 27 | at | Sioux Falls | 24 | OT | | GAC |