| 9/1/2016 | Urbana (3-8,2-8) | 24 | at | Glenville State | 44 | | | |
| 9/10/2016 | Glenville State | 31 | at | West Virginia Wesleyan (4-7,4-6) | 28 | | | |
| 9/17/2016 | Charleston WV (3-8,3-7) | 28 | at | Glenville State | 35 | | | |
| 9/24/2016 | Glenville State | 17 | at | Virginia-Wise (6-5,5-5) | 26 | | | |
| 10/1/2016 | Notre Dame OH (9-2,8-2) | 34 | at | Glenville State | 28 | | | |
| 10/8/2016 | Glenville State | 7 | at | Shepherd (13-1,10-0) | 38 | | | |
| 10/13/2016 | Alderson-Broaddus (7-2) | 19 | at | Glenville State | 7 | | | D2Ind |
| 10/22/2016 | West Virginia State (3-8,3-7) | 26 | at | Glenville State | 43 | | | |
| 10/29/2016 | Glenville State | 19 | at | Concord (2-9,2-8) | 8 | | | |
| 11/3/2016 | West Liberty (4-7,4-6) | 41 | at | Glenville State | 24 | | | |
| 11/10/2016 | Glenville State | 30 | at | Fairmont State (10-2,9-1) | 37 | | | |