| 9/3/2016 | Fairmont State | 30 | at | West Virginia State (3-8,3-7) | 20 | | | |
| 9/10/2016 | Concord (2-9,2-8) | 0 | at | Fairmont State | 28 | | | |
| 9/15/2016 | Fairmont State | 21 | at | West Liberty (4-7,4-6) | 20 | | | |
| 9/22/2016 | Fairmont State | 16 | at | Alderson-Broaddus (7-2) | 3 | | | at D2Ind |
| 10/1/2016 | Urbana (3-8,2-8) | 14 | at | Fairmont State | 48 | | | |
| 10/8/2016 | Fairmont State | 31 | at | West Virginia Wesleyan (4-7,4-6) | 17 | | | |
| 10/13/2016 | Charleston WV (3-8,3-7) | 13 | at | Fairmont State | 21 | | | |
| 10/22/2016 | Fairmont State | 58 | at | Virginia-Wise (6-5,5-5) | 3 | | | |
| 10/27/2016 | Notre Dame OH (9-2,8-2) | 19 | at | Fairmont State | 23 | | | |
| 11/5/2016 | Fairmont State | 17 | at | Shepherd (13-1,10-0) | 27 | | | |
| 11/10/2016 | Glenville State (5-6,5-5) | 30 | at | Fairmont State | 37 | | | |
| 11/19/2016 | Indiana PA (10-2) | 62 | at | Fairmont State | 13 | | | PSAC |