| 9/1/2016 | Kentucky Wesleyan (3-8) | 29 | at | Delta State | 50 | D2Ind | ||
| 9/10/2016 | Texas A&M-Commerce (10-2) | 40 | at | Delta State | 28 | LSC | ||
| 9/17/2016 | Delta State | 24 | at | West Georgia (7-4,4-4) | 34 | |||
| 9/24/2016 | Shorter (0-11,0-8) | 7 | at | Delta State | 47 | |||
| 9/29/2016 | Mississippi College (3-7,1-7) | 31 | at | Delta State | 61 | |||
| 10/8/2016 | Delta State | 42 | at | West Alabama (7-4,6-2) | 54 | |||
| 10/15/2016 | West Florida (5-6,3-5) | 51 | at | Delta State | 55 | |||
| 10/22/2016 | Delta State | 27 | at | Valdosta State (8-3,6-2) | 56 | |||
| 10/29/2016 | North Alabama (11-2,7-0) | 49 | at | Delta State | 19 | |||
| 11/12/2016 | Delta State | 16 | at | Florida Tech (8-3,5-2) | 42 |
| vs Delta State | vs Other Opponents | Delta State compared to OOs | |
| Record: | 6-4 | 56-46 | |
| Points Scored: | 39.30 | 29.06 | -10.24 |
| Points Allowed: | 36.90 | 25.97 | 10.93 |
| Margin: | 2.40 | 3.09 | 0.69 |
| Total Points: | 76.20 | 55.03 | 21.17 |