| 9/1/2016 | Duquesne | 10 | at | Youngstown State (12-4) | 45 | at MVC | ||
| 9/10/2016 | Bucknell (4-7) | 19 | at | Duquesne | 30 | Pat | ||
| 9/17/2016 | Dayton (9-2) | 20 | at | Duquesne | 34 | Pio | ||
| 9/24/2016 | Kennesaw St (8-3) | 36 | at | Duquesne | 28 | BigS | ||
| 10/1/2016 | Duquesne | 54 | at | Jacksonville (5-5) | 35 | at Pio | ||
| 10/15/2016 | Robert Morris (2-9,1-5) | 24 | at | Duquesne | 31 | |||
| 10/21/2016 | Duquesne | 10 | at | St Francis PA (7-5,5-1) | 14 | |||
| 10/29/2016 | Bryant (5-6,4-2) | 31 | at | Duquesne | 35 | |||
| 11/5/2016 | Duquesne | 28 | at | Wagner (6-5,4-2) | 20 | |||
| 11/12/2016 | Sacred Heart (6-5,1-5) | 10 | at | Duquesne | 31 | |||
| 11/19/2016 | Duquesne | 52 | at | Central Conn (2-9,1-5) | 19 |
| vs Duquesne | vs Other Opponents | Duquesne compared to OOs | |
| Record: | 3-8 | 63-52 | |
| Points Scored: | 24.82 | 26.92 | 2.10 |
| Points Allowed: | 31.18 | 23.73 | 7.45 |
| Margin: | -6.36 | 3.19 | 9.55 |
| Total Points: | 56.00 | 50.65 | 5.35 |