| 9/2/2016 | Lafayette | 24 | at | Central Conn | 10 | @ NE | ||
| Colgate | 7 | at | Syracuse | 33 | @ ACC (1A) | |||
| 9/3/2016 | Davidson | 14 | at | Georgetown | 38 | Pio | ||
| Monmouth NJ | 23 | at | Lehigh | 21 | BigS | |||
| Bucknell | 26 | at | Marist | 10 | @ Pio | |||
| Holy Cross | 51 | at | Morgan State | 24 | @ MEAC | |||
| Fordham | 16 | at | Navy | 52 | @ AAC (1A) | |||
| 9/10/2016 | Bucknell | 19 | at | Duquesne | 30 | @ NE | ||
| Elizabeth City State | 21 | at | Fordham | 83 | CIAA (D2) | |||
| Delaware | 24 | at | Lafayette | 6 | CAAF | |||
| Georgetown | 20 | at | Marist | 17 | @ Pio | |||
| Holy Cross | 28 | at | New Hampshire | 39 | @ CAAF | |||
| Lehigh | 21 | at | Villanova | 26 | @ CAAF | |||
| 9/17/2016 | Holy Cross | 28 | at | Albany NY | 45 | @ CAAF | ||
| Cornell | 24 | at | Bucknell | 16 | Ivy | |||
| Lehigh | 49 | at | Pennsylvania | 28 | @ Ivy | |||
| Lafayette | 31 | at | Princeton | 35 | @ Ivy | |||
| Colgate | 55 | at | Yale | 13 | @ Ivy | |||
| 9/24/2016 | VMI | 23 | at | Bucknell | 17 | SoCon | ||
| Pennsylvania | 17 | at | Fordham | 31 | Ivy | |||
| Columbia | 14 | at | Georgetown | 17 | Ivy | |||
| Dartmouth | 35 | at | Holy Cross | 10 | Ivy | |||
| Villanova | 31 | at | Lafayette | 14 | CAAF | |||
| Princeton | 28 | at | Lehigh | 42 | Ivy | |||
| Colgate | 31 | at | Richmond | 38 | @ CAAF | |||
| 9/30/2016 | Georgetown | 17 | at | Harvard | 31 | @ Ivy | ||
| 10/1/2016 | Cornell | 39 | at | Colgate | 38 | Ivy | ||
| Holy Cross | 38 | at | Lafayette | 28 | ||||
| Fordham | 41 | at | Monmouth NJ | 42 | OT | @ BigS | ||
| Lehigh | 63 | at | Yale | 35 | @ Ivy | |||
| 10/8/2016 | Lafayette | 34 | at | Fordham | 58 | |||
| Princeton | 31 | at | Georgetown | 17 | Ivy | |||
| Bucknell | 21 | at | Holy Cross | 20 | ||||
| Colgate | 31 | at | Lehigh | 45 | ||||
| 10/15/2016 | Lafayette | 7 | at | Army | 62 | @ Ind (1A) | ||
| Colgate | 27 | at | Bucknell | 7 | ||||
| Yale | 37 | at | Fordham | 44 | Ivy | |||
| Lehigh | 35 | at | Georgetown | 3 | ||||
| Harvard | 17 | at | Holy Cross | 27 | Ivy | |||
| 10/22/2016 | Lafayette | 17 | at | Bucknell | 42 | |||
| Georgetown | 14 | at | Fordham | 17 | ||||
| Lehigh | 46 | at | Holy Cross | 14 | ||||
| 10/29/2016 | Bucknell | 28 | at | Charleston Southern | 49 | @ BigS | ||
| Holy Cross | 8 | at | Colgate | 26 | ||||
| Georgetown | 3 | at | Lafayette | 17 | ||||
| Fordham | 37 | at | Lehigh | 58 | ||||
| 11/5/2016 | Colgate | 20 | at | Fordham | 24 | |||
| Holy Cross | 21 | at | Georgetown | 20 | ||||
| Bucknell | 13 | at | Lehigh | 20 | ||||
| 11/12/2016 | Lafayette | 17 | at | Colgate | 38 | |||
| Bucknell | 21 | at | Georgetown | 7 | ||||
| Fordham | 54 | vs | Holy Cross | 14 | Bronx NY | |||
| 11/19/2016 | Fordham | 36 | at | Bucknell | 22 | |||
| Georgetown | 10 | at | Colgate | 38 | ||||
| Lehigh | 45 | at | Lafayette | 21 | ||||
| 11/26/2016 | Lehigh | 21 | at | New Hampshire | 64 | @ CAAF |